AP20187

AP20187 is a ligand that can induce homodimerization of fusion proteins containing the F36V mutant of an FKBP domain(FKBPF36V),[1] available commercially as the DmrB domain.[2][3]

References

  1. ↑ Kawahara, Masahiro; Mabe, Satoru; Nagamune, Teruyuki. "Detecting protein–protein interactions based on kinase-mediated growth induction of mammalian cells". Nature Scientific Reports. doi:10.1038/srep06127.
  2. ↑ "Dimerizer Ligands - B/B Homodimerizer (AP20187), A/C Heterodimerizer (AP21967), D/D Solubilizer (AP21998), B/B Washout Ligand". Clontech.com. Retrieved February 5, 2016.
  3. ↑ "AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice. - PubMed - NCBI". Ncbi.nlm.nih.gov. Retrieved February 5, 2016.


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