Aschoff cell

In pathology, Aschoff (or Aschoff giant cells) cells are often cells associated with rheumatic heart disease. They are found in Aschoff bodies surrounding centres of fibrinoid necrosis.
In comparison with Anitschkow cells their cytoplasm is more basophilic, can contain more up to 4 nuclei.^[1]
Aschoff believed that Aschoff giant cells were some type of connective or endothelial tissue.^[2] Today are Aschoff cells considered to be derived from cardiac myocytes rather than connective tissue cells.^[1]

Aschoff cells were named after the German physician and pathologist Ludwig Aschoff.

References

1 2 Aschoff Body. [online]. [cit. 2014-02-25]. Retrieved from http://www.histopathology-india.net/Asch.htm
↑ MCGUIRE, John. W. a Bernice G. WEDUM. ORIGIN OF THE ASCHOFF BODY. [online]. [cit. 2014-02-25]. Retrieved from http://ard.bmj.com/content/22/3/127.full.pdf

Heart murmur	Systolic heart murmur: Benign paediatric heart murmur (Still's murmur) Diastolic heart murmur: Pulmonic regurgitation (Graham Steell murmur) Aortic insufficiency (Austin Flint murmur) Carey Coombs murmur Mitral regurgitation (Presystolic murmur)

Aortic insufficiency	Watson's water hammer pulse/Corrigan pulse De Musset's sign Duroziez's sign Müller's sign Quincke's sign Austin Flint murmur Mayne's sign

Other endocardium	endocarditis: Roth's spot Janeway lesion/Osler's node Bracht-Wachter bodies

Pericardium	Cardiac tamponade/Pericardial effusion: Beck's triad Ewart's sign

Other	rheumatic fever: Anitschkow cell Aschoff body EKG (Osborn wave) angina pectoris (Levine's sign) Gallavardin phenomenon

Arterial	aortic aneurysm (Cardarelli's sign, Oliver's sign) pulmonary embolism (McConnell's sign) radial artery sufficiency (Allen's test) pseudohypertension (Osler's sign) thrombus (Lines of Zahn) Adson's sign arteriovenous fistula (Nicoladoni sign)

Venous	Friedreich's sign Caput medusae Kussmaul's sign DVT Bancroft's sign Homans sign Lisker's sign Louvel's sign Lowenberg's sign Peabody's sign Pratt's sign Rose's sign Trendelenburg test superior vena cava syndrome (Pemberton's sign)

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