Benzathine benzylpenicillin
 | |
| Combination of | |
|---|---|
| Benzylpenicillin | Antibiotic |
| Benzathine | Stabilizer |
| Clinical data | |
| AHFS/Drugs.com | International Drug Names |
| ATC code | J01CE08 (WHO) |
| Identifiers | |
| CAS Number |
1538-09-6  |
| PubChem (CID) | 15232 |
| ChemSpider |
14498 |
| UNII |
SSZ1S4I0US |
| ChEBI |
CHEBI:51352 |
| ChEMBL |
CHEMBL1200651 |
| E number | E708 (antibiotics) |
 (what is this?) (verify) | |
Benzathine benzylpenicillin (rINN) is a form of penicillin also known as benzathine penicillin. It is an antibiotic useful for the treatment of a number of bacterial infections.
It is slowly absorbed into the circulation, after intramuscular injection, and hydrolysed to benzylpenicillin in vivo. It is the drug-of-choice when prolonged low concentrations of benzylpenicillin are required and appropriate, allowing prolonged antibiotic action over 2–4 weeks after a single IM dose. It is marketed by Pfizer (formerly by Wyeth) under the trade name Bicillin L-A.
Medical uses for benzathine penicillin include: prevention of rheumatic fever and early or latent syphilis.[1]
It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.[2]
Adverse effects
Compendial status
References
- ↑ Rossi S, editor, ed. (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3.
- ↑ "WHO Model List of EssentialMedicines" (PDF). World Health Organization. October 2013. Retrieved 22 April 2014.
- ↑ British Pharmacopoeia Commission Secretariat. "Index (BP 2009)" (PDF). Archived from the original (PDF) on 11 April 2009. Retrieved 26 March 2010.