Benzoyl-CoA 2,3-dioxygenase

Benzoyl-CoA 2,3-dioxygenase
Identifiers
EC number 1.14.12.21
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Benzoyl-CoA 2,3-dioxygenase (EC 1.14.12.21, benzoyl-CoA dioxygenase/reductase, BoxBA, BoxA/BoxB system) is an enzyme with systematic name benzoyl-CoA,NADPH:oxygen oxidoreductase (2,3-hydroxylating).[1][2][3] This enzyme catalyses the following chemical reaction

benzoyl-CoA + NADPH + H+ + O2 2,3-dihydro-2,3-dihydroxybenzoyl-CoA + NADP+

Benzoyl-CoA 2,3-dioxygenase is involved in aerobic benzoate metabolism in Azoarcus evansii.

References

  1. Zaar, A.; Gescher, J.; Eisenreich, W.; Bacher, A.; Fuchs, G. (2004). "New enzymes involved in aerobic benzoate metabolism in Azoarcus evansii". Mol. Microbiol. 54 (1): 223–238. doi:10.1111/j.1365-2958.2004.04263.x. PMID 15458418.
  2. Gescher, J.; Zaar, A.; Mohamed, M.; Schagger, H.; Fuchs, G. (2002). "Genes coding for a new pathway of aerobic benzoate metabolism in Azoarcus evansii". J. Bacteriol. 184 (22): 6301–6315. doi:10.1128/jb.184.22.6301-6315.2002. PMC 151953Freely accessible. PMID 12399500.
  3. Mohamed, M.E.; Zaar, A.; Ebenau-Jehle, C.; Fuchs, G. (2001). "Reinvestigation of a new type of aerobic benzoate metabolism in the proteobacterium Azoarcus evansii". J. Bacteriol. 183 (6): 1899–1908. doi:10.1128/JB.183.6.1899-1908.2001. PMC 95084Freely accessible. PMID 11222587.

External links

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