CDH9

CDH9
Identifiers
Aliases	CDH9
External IDs	MGI: 107433 HomoloGene: 9450 GeneCards: CDH9
Genetically Related Diseases
coronary artery disease[1]
Gene ontology Molecular function • calcium ion binding • molecular function • metal ion binding Cellular component • integral component of membrane • plasma membrane • membrane Biological process • single organismal cell-cell adhesion • cell adhesion • adherens junction organization • homophilic cell adhesion via plasma membrane adhesion molecules Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	1007	12565
Ensembl	ENSG00000113100	ENSMUSG00000025370
UniProt	Q9ULB4	P70407
RefSeq (mRNA)	NM_016279	NM_009869
RefSeq (protein)	NP_057363.3	n/a
Location (UCSC)	Chr 5: 26.88 – 27.12 Mb	Chr 15: 16.78 – 16.86 Mb
PubMed search	[2]	[3]
Wikidata

View/Edit Human

View/Edit Mouse

Cadherin 9 is a protein that in humans is encoded by the CDH9 gene.^[4][5]

Clinical significance

An association with autism has been suggested.^[6]

See also

• Cadherin
• Heritability of autism

References

1. "Diseases that are genetically associated with CDH9 view/edit references on wikidata".
2. "Human PubMed Reference:".
3. "Mouse PubMed Reference:".
4. "Entrez Gene: cadherin 9".
5. Suzuki S, Sano K, Tanihara H (April 1991). "Diversity of the cadherin family: evidence for eight new cadherins in nervous tissue". Cell Regulation. 2 (4): 261–70. doi:10.1091/mbc.2.4.261. PMC 361775. PMID 2059658.
6. Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, et al. (May 2009). "Common genetic variants on 5p14.1 associate with autism spectrum disorders". Nature. 459 (7246): 528–33. doi:10.1038/nature07999. PMC 2943511. PMID 19404256.

Further reading

• Nollet F, Kools P, van Roy F (June 2000). "Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members". Journal of Molecular Biology. 299 (3): 551–72. doi:10.1006/jmbi.2000.3777. PMID 10835267.
• Shimoyama Y, Tsujimoto G, Kitajima M, Natori M (July 2000). "Identification of three human type-II classic cadherins and frequent heterophilic interactions between different subclasses of type-II classic cadherins". The Biochemical Journal. 349 (Pt 1): 159–67. doi:10.1042/0264-6021:3490159. PMC 1221133. PMID 10861224.
• Wang K, Zhang H, Bloss CS, Duvvuri V, Kaye W, Schork NJ, Berrettini W, Hakonarson H (September 2011). "A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa". Molecular Psychiatry. 16 (9): 949–59. doi:10.1038/mp.2010.107. PMID 21079607.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ali J, Liao F, Martens E, Muller WA (June 1997). "Vascular endothelial cadherin (VE-cadherin): cloning and role in endothelial cell-cell adhesion". Microcirculation. 4 (2): 267–77. doi:10.3109/10739689709146790. PMID 9219219.
• Thedieck C, Kalbacher H, Kuczyk M, Müller GA, Müller CA, Klein G (2007). Zoccali C, ed. "Cadherin-9 is a novel cell surface marker for the heterogeneous pool of renal fibroblasts". PloS One. 2 (7): e657. doi:10.1371/journal.pone.0000657. PMC 1924602. PMID 17668045.
• Hülsken J, Birchmeier W, Behrens J (December 1994). "E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton". The Journal of Cell Biology. 127 (6 Pt 2): 2061–9. doi:10.1083/jcb.127.6.2061. PMC 2120290. PMID 7806582.