CENPK

CENPK
Identifiers
Aliases	CENPK, AF5alpha, CENP-K, P33, Solt, FKSG14, centromere protein K
External IDs	MGI: 1926210 HomoloGene: 11035 GeneCards: CENPK
Gene ontology Molecular function • protein binding Cellular component • cytosol • nucleus • nucleoplasm • condensed chromosome kinetochore • chromosome, centromeric region • chromosome • kinetochore Biological process • CENP-A containing nucleosome assembly • sister chromatid cohesion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	64105	60411
Ensembl	ENSG00000123219	ENSMUSG00000021714
UniProt	Q9BS16	Q9ESN5
RefSeq (mRNA)	NM_001267038 NM_022145	NM_021790 NM_181061
RefSeq (protein)	NP_001253967.1 NP_071428.2	NP_068562.1 NP_851406.1
Location (UCSC)	Chr 5: 65.52 – 65.56 Mb	Chr 13: 104.23 – 104.25 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Centromere protein K is a protein that in humans is encoded by the CENPK gene.^[3][4]

Interactions

CENPK has been shown to interact with SOX6.^[5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Taki T, Hayashi Y, Taniwaki M, Seto M, Ueda R, Hanada R, Suzukawa K, Yokota J, Morishita K (Nov 1996). "Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia". Oncogene. 13 (10): 2121–30. PMID 8950979.
4. "Entrez Gene: CENPK centromere protein K".
5. Yamashita A, Ito M, Takamatsu N, Shiba T (Sep 2000). "Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147–51. doi:10.1016/S0014-5793(00)01987-6. PMID 10996314.

Further reading

• Izuta H, Ikeno M, Suzuki N, Tomonaga T, Nozaki N, Obuse C, Kisu Y, Goshima N, Nomura F, Nomura N, Yoda K (Jun 2006). "Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells". Genes to Cells. 11 (6): 673–84. doi:10.1111/j.1365-2443.2006.00969.x. PMID 16716197.
• Okada M, Cheeseman IM, Hori T, Okawa K, McLeod IX, Yates JR, Desai A, Fukagawa T (May 2006). "The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres". Nature Cell Biology. 8 (5): 446–57. doi:10.1038/ncb1396. PMID 16622420.
• Foltz DR, Jansen LE, Black BE, Bailey AO, Yates JR, Cleveland DW (May 2006). "The human CENP-A centromeric nucleosome-associated complex". Nature Cell Biology. 8 (5): 458–69. doi:10.1038/ncb1397. PMID 16622419.
• Obuse C, Yang H, Nozaki N, Goto S, Okazaki T, Yoda K (Feb 2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase". Genes to Cells. 9 (2): 105–20. doi:10.1111/j.1365-2443.2004.00705.x. PMID 15009096.
• Yamashita A, Ito M, Takamatsu N, Shiba T (Sep 2000). "Characterization of Solt, a novel SoxLZ/Sox6 binding protein expressed in adult mouse testis". FEBS Letters. 481 (2): 147–51. doi:10.1016/S0014-5793(00)01987-6. PMID 10996314.