CIAO1

CIAO1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3FM0
Identifiers
Aliases	CIAO1, CIA1, WDR39, cytosolic iron-sulfur assembly component 1
External IDs	MGI: 1346998 HomoloGene: 55850 GeneCards: CIAO1
Gene ontology Molecular function • protein binding Cellular component • CIA complex • MMXD complex Biological process • regulation of transcription from RNA polymerase II promoter • iron-sulfur cluster assembly • positive regulation of cell proliferation • chromosome segregation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	9391	26371
Ensembl	ENSG00000144021	ENSMUSG00000003662
UniProt	O76071	Q99KN2
RefSeq (mRNA)	NM_004804	NM_025296
RefSeq (protein)	NP_004795.1	NP_079572.2
Location (UCSC)	Chr 2: 96.27 – 96.27 Mb	Chr 2: 127.24 – 127.25 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Probable cytosolic iron-sulfur protein assembly protein CIAO1 is a protein that in humans is encoded by the CIAO1 gene.^[3][4][5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Johnstone RW, Wang J, Tommerup N, Vissing H, Roberts T, Shi Y (Jun 1998). "Ciao 1 is a novel WD40 protein that interacts with the tumor suppressor protein WT1". J Biol Chem. 273 (18): 10880–7. doi:10.1074/jbc.273.18.10880. PMID 9556563.
4. Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T, Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL, Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD (Nov 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
5. "Entrez Gene: CIAO1 cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID 17041588.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.