Carotenoid 1,2-hydratase

"CrtC" redirects here. For uses of the acronym CRTC, see CRTC (disambiguation).
Carotenoid 1,2-hydratase
Identifiers
EC number 4.2.1.131
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Carotenoid 1,2-hydratase (EC 4.2.1.131, CrtC) is an enzyme with systematic name lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming).[1][2] This enzyme catalyses the following chemical reaction

(1) 1-hydroxy-1,2-dihydrolycopene lycopene + H2O
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene 1-hydroxy-1,2-dihydrolycopene + H2O

In Rubrivivax gelatinosus and Thiocapsa roseopersicina both products are formed.

References

  1. Steiger, S.; Mazet, A.; Sandmann, G. (2003). "Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus". Arch. Biochem. Biophys. 414 (1): 51–58. doi:10.1016/s0003-9861(03)00099-7. PMID 12745254.
  2. Hiseni, A.; Arends, I.W.; Otten, L.G. (2011). "Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina". Appl. Microbiol. Biotechnol. 91 (4): 1029–36. doi:10.1007/s00253-011-3324-1. PMID 21590288.

External links

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