Delta1-piperideine-2-carboxylate reductase
delta1-piperideine-2-carboxylate reductase | |||||||||
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Identifiers | |||||||||
EC number | 1.5.1.21 | ||||||||
CAS number | 52037-88-4 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a Delta1-piperideine-2-carboxylate reductase (EC 1.5.1.21) is an enzyme that catalyzes the chemical reaction
- L-pipecolate + NADP+ Delta1-piperideine-2-carboxylate + NADPH + H+
Thus, the two substrates of this enzyme are L-pipecolate and NADP+, whereas its 3 products are Delta1-piperideine-2-carboxylate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-pipecolate:NADP+ 2-oxidoreductase. Other names in common use include 1,2-didehydropipecolate reductase, P2C reductase, and 1,2-didehydropipecolic reductase. This enzyme participates in lysine degradation.
References
- Payton CW, Chang YF (1982). "delta1-piperideine-2-carboxylate reductase of Pseudomonas putida". J. Bacteriol. 149 (3): 864–71. PMC 216472. PMID 6801013.
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