Dihydrokavain

Dihydrokavain

Names
IUPAC name 4-methoxy-2-phenethyl-2,3-dihydropyran-6-one
Other names Dihydrokawain Marindinin
Identifiers
CAS Number	587-63-3 19451-52-6 19902-90-0 24576-85-0 3384-26-7
3D model (Jmol)	Interactive image
ChemSpider	88817
PubChem	98356
InChI InChI=1S/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6,10,12H,7-9H2,1H3 Key: VOOYTQRREPYRIW-UHFFFAOYSA-N InChI=1/C14H16O3/c1-16-13-9-12(17-14(15)10-13)8-7-11-5-3-2-4-6-11/h2-6,10,12H,7-9H2,1H3 Key: VOOYTQRREPYRIW-UHFFFAOYAX
SMILES COC1=CC(=O)OC(C1)CCC2=CC=CC=C2
Properties
Chemical formula	C14H16O3
Molar mass	232.27 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Dihydrokavain is one of the six major kavalactones found in the kava plant.^[1] It appears to contribute significantly to the anxiolytic effects of kava, based on a study in chicks.^[2]

References

1. Malani, Joji (2002-12-03). "Evaluation of the effects of Kava on the Liver" (PDF). Fiji School of Medicine. Retrieved 2009-09-04.
2. Feltenstein, MW; LC Lambdin; M Ganzera; H Ranjith; W Dharmaratne; NP Nanayakkara; IA Khan; KJ Sufka (March 2003). "Anxiolytic properties of Piper methysticum extract samples and fractions in the chick social-separation-stress procedure.". Phytotherapy Research: PTR. 17 (3): 210–216. doi:10.1002/ptr.1107. PMID 12672148.