EFCAB6

EFCAB6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1WLZ, 5D67
Identifiers
Aliases	EFCAB6, DJBP, HSCBCIP1, dJ185D5.1, EF-hand calcium binding domain 6
External IDs	MGI: 1924877 HomoloGene: 11259 GeneCards: EFCAB6
Gene ontology Molecular function • metal ion binding • calcium ion binding Cellular component • nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	64800	77627
Ensembl	ENSG00000186976	ENSMUSG00000022441
UniProt	Q5THR3	Q6P1E8
RefSeq (mRNA)	NM_022785 NM_198856	NM_001161628 NM_001161629 NM_029946
RefSeq (protein)	NP_073622.2 NP_942153.1	NP_001155100.1 NP_001155101.1 NP_084222.4
Location (UCSC)	Chr 22: 43.53 – 43.81 Mb	Chr 15: 83.87 – 84.07 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

EF-hand calcium-binding domain-containing protein 6 is a protein that in humans is encoded by the EFCAB6 gene.^[3][4][5]

Interactions

EFCAB6 has been shown to interact with PARK7^[4] and Androgen receptor.^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O (Mar 2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.
4. Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (Mar 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex". Mol Cancer Res. 1 (4): 247–61. PMID 12612053.
5. "Entrez Gene: FLJ23588 CAP-binding protein complex interacting protein 1".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22.". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.