Eukaryotic initiation factor 4G

Eukaryotic initiation factor 4G, more commonly known as eIF4G, is an initiation factor involved in the assembly of the 43S and 48S pre-initiation complexes in eukaryotic cells, needed for protein synthesis. This particular initiation factor binds to the PABPI (PolyA binding protein I), which is in turn binds the messenger RNA's poly(A) tail and eIF3, which is bound to the incoming small ribosomal subunit (40S).[1]

References

  1. ↑ Lodish, Harvey; Berk, Arnold; Kaiser, Chris; Krieger, Monty; Bretscher, Anthony; Ploegh, Hidde; Amon, Angelika; Scott, Matthew. Molecular Cell Biology (Print) (7th ed.). New York: W. H. Freeman and Company. ISBN 978-1-4292-3413-9.
This article is issued from Wikipedia - version of the 6/11/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.