FAM62B

ESYT2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DMG, 4NPJ, 4NPK, 4P42
Identifiers
Aliases	ESYT2, CHR2SYT, E-Syt2, FAM62B, extended synaptotagmin protein 2, extended synaptotagmin 2
External IDs	MGI: 1261845 HomoloGene: 32699 GeneCards: ESYT2
Gene ontology Molecular function • calcium-dependent phospholipid binding • calcium ion binding • protein binding • metal ion binding • phosphatidylinositol binding • phosphatidylethanolamine binding • phosphatidylcholine binding • identical protein binding • lipid binding • cadherin binding involved in cell-cell adhesion Cellular component • intrinsic component of endoplasmic reticulum membrane • organelle membrane contact site • integral component of membrane • extrinsic component of cytoplasmic side of plasma membrane • plasma membrane • integral component of plasma membrane • endoplasmic reticulum membrane • membrane • endoplasmic reticulum • cell-cell adherens junction Biological process • lipid transport • endocytosis • transport • cell-cell adhesion Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	57488	52635
Ensembl	ENSG00000117868	ENSMUSG00000021171
UniProt	A0FGR8	Q3TZZ7
RefSeq (mRNA)	NM_020728	NM_028731
RefSeq (protein)	NP_065779.1	NP_083007.2
Location (UCSC)	Chr 7: 158.73 – 158.83 Mb	Chr 12: 116.28 – 116.37 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Extended synaptotagmin-2 is a protein that in humans is encoded by the ESYT2 gene.^[3][4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Craxton M (Sep 2007). "Evolutionary genomics of plant genes encoding N-terminal-TM-C2 domain proteins and the similar FAM62 genes and synaptotagmin genes of metazoans". BMC Genomics. 8: 259. doi:10.1186/1471-2164-8-259. PMC 1976326. PMID 17672888.
4. "Entrez Gene: FAM62B family with sequence similarity 62 (C2 domain containing) member B".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Nagase T, Ishikawa K, Kikuno R, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
• Craxton M (2001). "Genomic analysis of synaptotagmin genes.". Genomics. 77 (1-2): 43–9. doi:10.1006/geno.2001.6619. PMID 11543631.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Foster LJ, Rudich A, Talior I, et al. (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC).". J. Proteome Res. 5 (1): 64–75. doi:10.1021/pr0502626. PMID 16396496.