Fluorodopa
Identifiers | |
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Synonyms |
6-fluoro-L-DOPA FDOPA |
CAS Number | 75290-51-6 |
ChemSpider | 96897 |
UNII | 6WIZ27OUZ9 |
Chemical and physical data | |
Formula | C9H10FNO4 |
Molar mass | 215.18 g/mol |
3D model (Jmol) | Interactive image |
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Fluorodopa, also known as FDOPA, is a fluorinated form of L-DOPA primarily synthesized as its fluorine-18 isotopologue for use as a radiotracer in positron emission tomography.[1] FD PET is a valid method for assessing the functional state of the nigrostriatal dopaminergic pathway. It is particularly useful for studies requiring repeated measures such as examinations of the course of a disease and the effect of treatment
References
- ↑ -Deng WP, Wong KA, Kirk KL (2002). "Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA". Tetrahedron: Asymmetry. 13 (11): 1135–1140. doi:10.1016/S0957-4166(02)00321-X.
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