FinP

FinP
Predicted secondary structure and sequence conservation of FinP
Identifiers
Symbol FinP
Rfam RF00107
Other data
RNA type Gene
Domain(s) Bacteria
SO 0000644

FinP encodes an antisense non-coding RNA gene that is complementary to part of the TraJ 5' UTR. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.[1][2]

References

  1. Jerome, LJ; van Biesen T; Frost LS (1999). "Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E". J Mol Biol. 285 (4): 14571473. doi:10.1006/jmbi.1998.2404. PMID 9917389.
  2. Arthur, DC; Ghetu AF; Gubbins MJ; Edwards RA; Frost LS; Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J. 22 (23): 63466355. doi:10.1093/emboj/cdg607. PMC 291848Freely accessible. PMID 14633993.

External links

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