HOXA6

HOXA6
Identifiers
Aliases	HOXA6, HOX1, HOX1.2, HOX1B, homeobox A6
External IDs	MGI: 96178 HomoloGene: 7765 GeneCards: HOXA6
Gene ontology Molecular function • transcription factor activity, sequence-specific DNA binding • sequence-specific DNA binding • DNA binding Cellular component • nucleus Biological process • embryonic skeletal system morphogenesis • multicellular organism development • regulation of transcription, DNA-templated • transcription, DNA-templated • anterior/posterior pattern specification • embryonic skeletal system development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3203	15403
Ensembl	ENSG00000106006	ENSMUSG00000043219
UniProt	P31267	P09092
RefSeq (mRNA)	NM_024014	NM_010454
RefSeq (protein)	NP_076919.1	NP_034584.1
Location (UCSC)	Chr 7: 27.15 – 27.15 Mb	Chr 6: 52.21 – 52.21 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Homeobox protein Hox-A6 is a protein that in humans is encoded by the HOXA6 gene.^[3][4][5]

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.^[5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
4. Scott MP (Dec 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459.
5. "Entrez Gene: HOXA6 homeobox A6".

Further reading

• Boncinelli E, Acampora D, Pannese M, et al. (1990). "Organization of human class I homeobox genes". Genome. 31 (2): 745–56. doi:10.1139/g89-133. PMID 2576652.
• Apiou F, Flagiello D, Cillo C, et al. (1996). "Fine mapping of human HOX gene clusters". Cytogenet. Cell Genet. 73 (1–2): 114–5. doi:10.1159/000134320. PMID 8646877.
• Walters JR, Howard A, Rumble HE, et al. (1997). "Differences in expression of homeobox transcription factors in proximal and distal human small intestine". Gastroenterology. 113 (2): 472–7. doi:10.1053/gast.1997.v113.pm9247466. PMID 9247466.
• Kosaki K, Kosaki R, Suzuki T, et al. (2002). "Complete mutation analysis panel of the 39 human HOX genes". Teratology. 65 (2): 50–62. doi:10.1002/tera.10009. PMID 11857506.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.