Harmol
 | |
| Names | |
|---|---|
| IUPAC name
1-methyl-2,9-dihydropyrido[3,4-b]indol-7-one | |
| Identifiers | |
| 487-03-6 | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 10296888 |
| ECHA InfoCard | 100.006.951 |
| PubChem | 68094 |
| |
| Properties | |
| C12H10N2O | |
| Molar mass | 198.22 g/mol |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Harmol is a β-carboline isolated from nature.[1][2][3]
References
- ↑ Abe A, Kokuba H (2013). "Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin.". Oncol Rep. 29 (4): 1333–42. doi:10.3892/or.2013.2242. PMID 23338618.
- ↑ El Gendy MA, Soshilov AA, Denison MS, El-Kadi AO (2012). "Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol.". Toxicol Lett. 208 (1): 51–61. doi:10.1016/j.toxlet.2011.09.030. PMC 3263333
. PMID 22001777. - ↑ Abe A, Yamada H, Moriya S, Miyazawa K (2011). "The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells.". Biol Pharm Bull. 34 (8): 1264–72. PMID 21804216.
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