Hemoglobin J

Hemoglobin J is an abnormal hemoglobin, an alpha globin gene variant and present in various geographic locations. It was first reported in American Negro family[1] in 1956. Later on reported from Indonsia, India, and other parts of the world. Hemoglobin J reported from Meerut India shows the mutation of 120th Alanine to Glutamic acid on alpha chain.[2] Hemoglobin J was also reported from Chhattisgarh, Central India as revealed by Lingojwar and coworkers in 2016.

References

  1. ↑ Thorup, O (1956). "Hemoglobin j" (PDF). Science. Retrieved 13 April 2016.
  2. ↑ Blackwell, R (May 10, 1974). "Hemoglobin J Meerut: alpha120 Ala leads to Glu". Biochim Biophys Acta. PMID 4600474.
This article is issued from Wikipedia - version of the 12/4/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.