Henry Kronenberg

Henry Kronenberg (fl. 2000s) is an American physician and academic. As of 2006 he is Division Head of Endocrinology at the Massachusetts General Hospital in Boston, MA and a Professor of Medicine at the Harvard Medical School. He is noted for his work on parathyroid hormone and the use of genetic mouse models to understand the role of parathyroid hormone and parathyroid hormone-related protein in the regulation of bone formation and remodeling.

Accomplishments

Dr. Kronenberg has made a series of fundamental observations of importance to the understanding of how several peptides regulate the formation and remodeling of bone. These include the cloning of a cDNA for parathyroid hormone,[1] the identification of a role for parathyroid hormone-related protein in endochondral ossification through Indian hedgehog (IHH) activation,[2][3] and studies that identified a role for parathyroid hormone in the regulation of the bone marrow stem cell niche.[4]

He has served as the President of the American Society for Bone and Mineral Research. He was a member of the Board of Advisors of the Rolanette and Berdon Lawrence Bone Disease Program of Texas from 2006-2012.

Dr. Kronenberg is the President-Elect of the Endocrine Society.

References

  1. ↑ Cloning and nucleotide sequence of DNA coding for bovine preproparathyroid hormone. Kronenberg HM, McDevitt BE, Majzoub JA, Nathans J, Sharp PA, Potts JT Jr, Rich A. Proc Natl Acad Sci U S A. 1979 Oct;76(10):4981-5
  2. ↑ Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP. Development. 2004 Mar;131(6):1309-18.
  3. ↑ Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy. Mak KK, Kronenberg HM, Chuang PT, Mackem S, Yang Y. Development. 2008 Jun;135(11):1947-56.
  4. ↑ Osteoblastic cells regulate the haematopoietic stem cell niche. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT. Nature. 2003 October 23;425(6960):841-6
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