Heptabarb

Heptabarb

Clinical data
Pregnancy category	?
Routes of administration	Oral[1]
ATC code	N05CA11 (WHO)
Legal status
Legal status	CA: Schedule IV ?
Pharmacokinetic data
Bioavailability	83%[1]
Metabolism	Hepatic
Biological half-life	6.1-11.2 hours[1]
Excretion	Renal[1]
Identifiers
IUPAC name 5-cyclohept-1-en-1-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
Synonyms	G-475
CAS Number	509-86-4
PubChem (CID)	10518
DrugBank	DB01354
ChemSpider	10081
UNII	V10R70ML23
KEGG	C17725
ChEMBL	CHEMBL468837
ECHA InfoCard	100.007.371
Chemical and physical data
Formula	C13H18N2O3
Molar mass	250.294 g/mol
3D model (Jmol)	Interactive image
SMILES O=C1NC(=O)NC(=O)C1(/C2=C/CCCCC2)CC
InChI InChI=1S/C13H18N2O3/c1-2-13(9-7-5-3-4-6-8-9)10(16)14-12(18)15-11(13)17/h7H,2-6,8H2,1H3,(H2,14,15,16,17,18) Key:PAZQYDJGLKSCSI-UHFFFAOYSA-N
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Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.^[2][3] It was used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.^[2][3]

See also

• Barbiturate

References

1. Breimer DD, de Boer AG (December 1975). "Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology. 9 (2-3): 169–78. doi:10.1007/bf00614014. PMID 9299.
2. C. R Ganellin; D. J Triggle; F.. Macdonald (1997). Dictionary of pharmacological agents. CRC Press. p. 1003. ISBN 978-0-412-46630-4. Retrieved 26 November 2011.
3. Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 513. ISBN 978-3-88763-075-1. Retrieved 26 November 2011.