Klaus Lauer
Dr. Klaus Lauer (born 1950) is a German neuroepidemologist, mostly known for his work on multiple sclerosis (MS).
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Early life
Klaus Joachim Lauer was born in 1950 and studied medicine in Frankfurt (Germany) from 1968 to 1975. He became a resident in the Department of Neurology of Klinikum Darmstadt, the Academic Teaching Hospital of Frankfurt University (Akademisches Lehrkrankenhaus der Universitäten Frankfurt/Main und Heidelberg-Mannheim, a major healthcare institution in South Hesse. Besides clinical work, K. Lauer devoted most of his research to epidemiology, with a special focus on MS etiology.
Career
Early on, he published a series of five articles[1][2][3][4][5] on multiple sclerosis in the land of Hesse with Prof. Dr. med. Wolfgang Firnhaber, who had already been studying MS epidemiology in Göttingen and Darmstadt,[6] with support from the Hertie Foundation, the German Research Foundation and the Stifterverband für die Deutsche Wissenschaft. His lasting collaboration with Prof. Firnhaber, a longtime expert in MS prognostication[7][8][9] and geomedical aspects of MS,[10] provided K. Lauer with a solid background in geomedical investigation.[11][12]
In the mid 80's, Dr. Lauer launched a series of specialized reports in Scandinavia, starting with a study of multiple sclerosis in Western Norway published in Neurology.[13] He has been following Norvegian MS ever since [14][15] and has also coauthored epidemiological studies in Sweden with Anne-Marie Landtblom and Inger Boström.[16]
Like John Kurtzke,[17] Klaus J. Lauer has dedicated a large part of his work to the study of MS in the Faroe Islands,[18] starting with a 1986 article in the Journal of Neurology entitled "Some comments on the occurrence of multiple sclerosis in the Faroe Islands",[19] followed in 1988 by "Multiple sclerosis in relation to industrial and commercial activities in the Faroe Islands"[20] in the journal Neuroepidemiology, followed one year later by "Dietary changes in temporal relation to multiple sclerosis in the Faroe Islands: an evaluation of literary sources"[21] in the same journal.
![](../I/m/Faroe_stamp_536_world_war_2.jpg)
MS is generally considered a multifactorial disease,[22] in which genetic predispositions and environmental triggers combine to launch an autoimmune process. As an international expert on the environmental dimension of MS,[23] Dr. Lauer compiled a review in Expert Review of Neurotherapeutics.[24]
Since 1992, Dr Lauer has published a large number of epidemiological studies covering most west European countries,[25][26][26][27][28][29] Russia,[30] the USA,[31][32] Canada, some countries in Asia and the Middle-East,[33] with a special focus on dietary aspects of etiology.[34][35][35][36][37] Most recently, Klaus Lauer has focused again on MS in the Faroes [38][39] and has been involved as an expert in the steering committee of the EnviMS study, a major multi-countries study investigating the impact of environmental exposures on MS.[40][41][42] Dr Lauer is also one of the authors of a reference study of the cost of MS in Europe[43] and of several publications dealing with technical and methodological considerations in neuroepidemiology applied to multiple sclerosis.[44][45]
References
- ↑ Lauer K, Firnhaber W, Reining R, Leuchtweis B (October 1984). "Epidemiological investigations into multiple sclerosis in southern Hesse. I. Methodological problems and basic epidemiologic characteristics". Acta Neurologica Scandinavica. 70 (4): 257–65. doi:10.1111/j.1600-0404.1984.tb00823.x. PMID 6507035.
- ↑ Lauer K, Firnhaber W (October 1984). "Epidemiological investigations into multiple sclerosis in southern Hesse. II. The distribution of cases in relation to exogenous features". Acta Neurologica Scandinavica. 70 (4): 266–73. doi:10.1111/j.1600-0404.1984.tb00824.x. PMID 6507036.
- ↑ Lauer K, Firnhaber W (October 1985). "Epidemiological investigations into multiple sclerosis in Southern Hesse. III. The possible influence of occupation on the risk of disease". Acta Neurologica Scandinavica. 72 (4): 397–402. doi:10.1111/j.1600-0404.1985.tb00890.x. PMID 4082904.
- ↑ Lauer K, Firnhaber W (October 1985). "Epidemiological investigations into multiple sclerosis in Southern Hesse. IV. The influence of urban and rural environment on disease risk". Acta Neurologica Scandinavica. 72 (4): 403–6. doi:10.1111/j.1600-0404.1985.tb00891.x. PMID 4082905.
- ↑ Lauer K, Firnhaber W (July 1987). "Epidemiological investigations into multiple sclerosis in Southern Hesse. V. Course and prognosis". Acta Neurologica Scandinavica. 76 (1): 12–7. doi:10.1111/j.1600-0404.1987.tb03537.x. PMID 3498287.
- ↑ "Deutsches Ärzteblatt international: Multiple Sclerosis Registry in Germany – Results of the Extension Phase 2005/2006: Article of 30 Years Ago (25.04.2008)". Aerzteblatt.de. 2008-04-25. Retrieved 2015-04-01.
- ↑ Bauer HJ, Firnhaber W, Winkler W (March 1965). "Prognostic criteria in multiple sclerosis". Annals of the New York Academy of Sciences. 122: 542–51. doi:10.1111/j.1749-6632.1965.tb20234.x. PMID 14313511.
- ↑ Bauer H, Firnhaber W (July 1963). "Zur Leistungsprognose Multiple-Sklerose-Kranker" [On the prognosis of work capacity in patients with multiple sclerosis]. Deutsche Medizinische Wochenschrift (in German). 88: 1357–64. doi:10.1055/s-0028-1112108. PMID 13966928.
- ↑ Lauer K, Firnhaber W (February 1992). "Prognostic criteria in an epidemiological group of patients with multiple sclerosis: an exploratory study". Journal of Neurology. 239 (2): 93–7. doi:10.1007/BF00862981. PMID 1552310.
- ↑ Firnhaber W (May 1972). "[Multiple sclerosis. Methods and results of a geomedical study]". Fortschritte der Medizin (in German). 90 (14): 551–4. PMID 5072275.
- ↑ Poser S, Poser W, Schlaf G, et al. (November 1986). "Prognostic indicators in multiple sclerosis". Acta Neurologica Scandinavica. 74 (5): 387–92. doi:10.1111/j.1600-0404.1986.tb03531.x. PMID 3825497.
- ↑ Prange AJ, Lauer K, Poser S, et al. (1986). "Epidemiological aspects of multiple sclerosis: a comparative study of four centres in Europe". Neuroepidemiology. 5 (2): 71–9. doi:10.1159/000110816. PMID 3785525.
- ↑ Lauer K, Firnhaber W (September 1985). "Western Norway: a high-risk area for MS". Neurology. 35 (9): 1392. doi:10.1212/wnl.35.9.1392. PMID 4022391.
- ↑ Risberg G, Aarseth JH, Nyland H, Lauer K, Myhr KM, Midgard R (October 2011). "Prevalence and incidence of multiple sclerosis in Oppland County: a cross-sectional population-based study in a landlocked county of Eastern Norway". Acta Neurologica Scandinavica. 124 (4): 250–7. doi:10.1111/j.1600-0404.2010.01465.x. PMID 21143594.
- ↑ Lauer K (February 2006). "Multiple sclerosis in Nordland County". Tidsskrift for Den Norske Lægeforening. 126 (5): 637–8. PMID 16505886.
- ↑ Boström I, Landtblom AM, Lauer K (December 2011). "An ecological study of industry in a high-risk region of multiple sclerosis". Journal of the Neurological Sciences. 311 (1-2): 50–7. doi:10.1016/j.jns.2011.09.005. PMID 21982618.
- ↑ "Multiple Sclerosis". Web.stanford.edu. 1997-03-21. Retrieved 2015-04-01.
- ↑ Klaus Lauer. "Dietary Changes in Temporal Relation to Multiple Sclerosis in the Faroe Islands : An Evaluation of Literary Sources" (PDF). While-science-sleeps.com. Retrieved 2015-04-01.
- ↑ Lauer K (June 1986). "Some comments on the occurrence of multiple sclerosis in the Faroe Islands". Journal of Neurology. 233 (3): 171–3. doi:10.1007/BF00314427. PMID 3522812.
- ↑ Lauer K (1988). "Multiple sclerosis in relation to industrial and commercial activities in the Faroe Islands". Neuroepidemiology. 7 (4): 228–33. doi:10.1159/000110155. PMID 3264057.
- ↑ Lauer K (1989). "Dietary changes in temporal relation to multiple sclerosis in the Faroe Islands: an evaluation of literary sources". Neuroepidemiology. 8 (4): 200–6. doi:10.1159/000110183. PMID 2755551.
- ↑ Amy Maxmen. "Whodunit? | Multiple Sclerosis Discovery Forum". Msdiscovery.org. Retrieved 2015-04-01.
- ↑ Lauer K (1995). "Environmental associations with the risk of multiple sclerosis: the contribution of ecological studies". Acta Neurologica Scandinavica. Supplementum. 161: 77–88. doi:10.1111/j.1600-0404.1995.tb05861.x. PMID 7653250.
- ↑ Lauer K (March 2010). "Environmental risk factors in multiple sclerosis". Expert Review of Neurotherapeutics. 10 (3): 421–40. doi:10.1586/ern.10.7. PMID 20187864.
- ↑ Lauer, K (1988). "Sociogeographic factors and multiple sclerosis--an ecological study in 6 European countries". Neuroepidemiology. 7 (3): 122–9. doi:10.1159/000110145. PMID 3405364.
- 1 2 Lauer, K (1989). "Multiple sclerosis in relation to meat preservation in France and Switzerland". Neuroepidemiology. 8 (6): 308–15. doi:10.1159/000110199. PMID 2586701.
- ↑ "A factor-analytical study of the multiple sclerosis mortality in Hesse and Baden-Wuerttemberg, Germany". Journal of Public Health. 1: 319–327. 1993-12-01. doi:10.1007/BF02959681. Retrieved 2015-04-01.
- ↑ Lauer, K (1990). "Mortality of multiple sclerosis in relation to geographic factors in France". Neuroepidemiology. 9 (3): 113–7. doi:10.1159/000110759. PMID 2402320.
- ↑ Lauer, K (1989). "Risk of multiple sclerosis in relation to industrial activities: An ecological study in four European countries". Neuroepidemiology. 8 (1): 38–42. doi:10.1159/000110163. PMID 2911392.
- ↑ Gusev, E; Boiko, A; Lauer, K; Riise, T; Deomina, T (1996). "Environmental risk factors in MS: A case-control study in Moscow". Acta neurologica Scandinavica. 94 (6): 386–94. doi:10.1111/j.1600-0404.1996.tb00050.x. PMID 9017026.
- ↑ Lauer, K (1994). "The risk of multiple sclerosis in the U.S.A. In relation to sociogeographic features: A factor-analytic study". Journal of Clinical Epidemiology. 47 (1): 43–8. doi:10.1016/0895-4356(94)90032-9. PMID 8283194.
- ↑
- ↑ Lauer, K; Alter, M.; Kahana, E.; Zilber, N.; Miller, A. (2007). "Multiple sclerosis frequency in Israel's diverse populations". Neurology. 68 (4): 311; author reply 311. doi:10.1212/01.wnl.0000255650.40828.98. PMID 17242346.
- ↑ Lauer K (2014-11-12). "The food pattern in geographical relation to the risk of multiple sclerosis in the Mediterranean and Near East region". J Epidemiol Community Health. 45: 251–2. PMC 1060768
. PMID 1757770.
- 1 2 Klaus Lauer (1997-08-01). "Diet and multiple sclerosis". Neurology. Retrieved 2015-04-01.
- ↑ Lauer, K (1991). "The history of nitrite in human nutrition: A contribution from German cookery books". Journal of Clinical Epidemiology. 44 (3): 261–4. doi:10.1016/0895-4356(91)90037-a. PMID 1999685.
- ↑ "Dr. Klaus Joachim Lauer Biography – Webcast powered by - MULTIWEBCAST - State-of-the-art Webcast Services". Multiwebcast.com. Retrieved 2015-04-01.
- ↑ Klaus Lauer (2011-06-13). "Multiple sclerosis incidence in the Faroe Islands". Msj.sagepub.com. Retrieved 2015-04-01.
- ↑ "IJMS | Free Full-Text | Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits". Mdpi.com. doi:10.3390/ijms15033533. Retrieved 2015-04-01.
- ↑ "A questionnaire for multinational case-control studies of environmental risk factors in multiple sclerosis (EnvIMS-Q)". Acta Neurologica Scandinavica. 126: 43–50. 2012-12-20. doi:10.1111/ane.12032. Retrieved 2015-04-01.
- ↑ "Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study". Msj.sagepub.com. 2014-01-10. Retrieved 2015-04-01.
- ↑ "Abstractverwaltung Congrex". Registration.akm.ch. 2013-10-03. Retrieved 2015-04-01.
- ↑ Sobocki, P; Pugliatti, M; Lauer, K; Kobelt, G (2007). "Estimation of the cost of MS in Europe: Extrapolations from a multinational cost study". Multiple Sclerosis. 13 (8): 1054–64. doi:10.1177/1352458507077941. PMID 17623729.
- ↑ Wolfson, C; Granieri, E; Lauer, K (1997). "Case-control studies in multiple sclerosis". Neurology. 49 (2 Suppl 2): S5–14. doi:10.1212/WNL.49.2_Suppl_2.S5. PMID 9270687.
- ↑ Riise, T; Grønning, M; Fernández, O; Lauer, K; Midgard, R; Minderhoud, J. M.; Nyland, H; Pálffy, G; Poser, S; Aarli, J. A. (1992). "Early prognostic factors for disability in multiple sclerosis, a European multicenter study". Acta neurologica Scandinavica. 85 (3): 212–8. doi:10.1111/j.1600-0404.1992.tb04031.x. PMID 1575007.