Kolanticon
Kolanticon is the brand name of a multi-ingredient drug preparation marketed in the United Kingdom by Peckforton Pharmaceuticals. It is indicated for the treatment of irritable bowel syndrome (IBS), functional dyspepsia (indigestion) and the symptoms of peptic ulcer. It is also indicated for symptomatic relief in oesophagitis, hiatus hernia, gastritis and iatrogenic gastritis.
Kolanticon is a liquid suspension that is sold in 200ml and 500ml bottles. It is available as a pharmacy only medication.
Kolanticon contains four active ingredients, which are:
Dicycloverine – an antispasmodic, which relieves painful stomach cramps and spasms. It relaxes the muscle in the walls of the stomach and intestines by blocking muscarinic receptors that are found in the muscle. By blocking these receptors it prevents the chemical acetylcholine from activating them and causing contraction. This reduces muscle contractions and allows the stomach and intestines to relax, reducing painful cramps and spasms.
Simethicone – an antiflatulent, which reduces the amount of trapped wind in the gut. It brings together all the small bubbles of gas that are trapped in the gut to form a large bubble, which can then be expelled more easily. This helps to relieve pain and bloating caused by trapped wind.
Aluminium hydroxide and Magnesium oxide – antacids that reduce the acidity of the stomach’s juices. Too much stomach acid can cause symptoms of heartburn and indigestion, as well as irritating an inflamed stomach lining or a peptic ulcer. By binding to and neutralising excess acid, antacids help to relieve the symptoms of dyspepsia that are often experienced by patients with IBS [1] [2] [3] [4]
References
- ↑ Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. Agréus L, Svärdsudd K, Nyrén O, Tibblin G. Gastroenterology 1995;109(3):671–680.
- ↑ Functional dyspepsia and irritable bowel syndrome: is there a common pathophysiological basis? Holtmann G, Goebell H, Talley NJ. Am J Gastroenterol 1997;92:954–959.
- ↑ Irritable bowel syndrome in patients with dyspepsia: a community-based study in southern Europe. Caballero-Plasencia AM, Sofos-Kontoyannis S, et al. Eur J Gastroenterol Hepatol 1999;11(5):517–522.
- ↑ Overlapping upper and lower gastrointestinal symptoms in irritable bowel syndrome patients with constipation or diarrhea. Talley NJ, Dennis EH, Schettler-Duncan VA, et al. Am J Gastroenterol 2003;98(11):2454–2459.