List of unsolved problems in medicine

This article lists currently unsolved problems in medicine.

Problems or unknown causes for diseases

• Alzheimer's disease
• Acrocyanosis
• Bell's palsy
• Benign fasciculation syndrome
• Benign paroxysmal vertigo of childhood
• Calciphylaxis
• Cardiac syndrome X
• Cluster headache
• Copenhagen disease
• Cronkhite–Canada syndrome
• Dermatomyositis
• Cyclic vomiting syndrome
• Danubian endemic familial nephropathy
• Dialysis disequilibrium syndrome
• Exploding head syndrome
• Fibromyalgia
• Fields' disease
• Floating–Harbor syndrome
• Geographic tongue
• Granuloma annulare
• Idiopathic intracranial hypertension
• Irritable bowel syndrome
• Interstitial cystitis
• Kawasaki disease
• Lymphedema
• Mesoamerican nephropathy
• Mortimer's disease
• Myofascial pain syndrome
• Nodding disease
• Sweating sickness
• Pigmented villonodular synovitis
• Pityriasis rosea
• Prurigo nodularis
• SAPHO syndrome
• Sarcoidosis
• Sjögren's syndrome
• Spontaneous cerebrospinal fluid leak
• Stiff person syndrome
• Sudden infant death syndrome
• Synovial osteochondromatosis
• TEMPI syndrome
• Trigger finger
• Tropical sprue
• Villitis of unknown etiology

(Note: diseases for which the etiology is fully or partially understood, but for which effective treatments are not yet available, are not included on the list. Some cancers would fall into this category.)