Malonyl CoA reductase (malonate semialdehyde-forming)
| Malonyl CoA reductase (malonate semialdehyde-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.2.1.75 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Malonyl CoA reductase (malonate semialdehyde-forming) (EC 1.2.1.75, NADP-dependent malonyl CoA reductase, malonyl CoA reductase (NADP)) is an enzyme with systematic name malonate semialdehyde:NADP+ oxidoreductase (malonate semialdehyde-forming).[1][2][3][4] This enzyme catalyse the following chemical reaction
- malonate semialdehyde + CoA + NADP+ malonyl-CoA + NADPH + H+
Requires Mg2+. Catalyses the reduction of malonyl-CoA to malonate semialdehyde.
References
- ↑ Strauss, G.; Fuchs, G. (1993). "Enzymes of a novel autotrophic CO2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle". Eur. J. Biochem. 215: 633–643. doi:10.1111/j.1432-1033.1993.tb18074.x. PMID 8354269.
- ↑ Berg, I.A.; Kockelkorn, D.; Buckel, W.; Fuchs, G. (2007). "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea". Science. 318: 1782–1786. doi:10.1126/science.1149976. PMID 18079405.
- ↑ Alber, B.; Olinger, M.; Rieder, A.; Kockelkorn, D.; Jobst, B.; Hugler, M.; Fuchs, G. (2006). "Malonyl-coenzyme A reductase in the modified 3-hydroxypropionate cycle for autotrophic carbon fixation in archaeal Metallosphaera and Sulfolobus spp". J. Bacteriol. 188 (24): 8551–8559. doi:10.1128/JB.00987-06. PMC 1698253
. PMID 17041055. - ↑ Hugler, M.; Menendez, C.; Schagger, H.; Fuchs, G. (2002). "Malonyl-coenzyme A reductase from Chloroflexus aurantiacus, a key enzyme of the 3-hydroxypropionate cycle for autotrophic CO2 fixation". J. Bacteriol. 184 (9): 2404–2410. doi:10.1128/jb.184.9.2404-2410.2002. PMC 134993. PMID 11948153.
External links
- Malonyl CoA reductase (malonate semialdehyde-forming) at the US National Library of Medicine Medical Subject Headings (MeSH)
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