Meningioangiomatosis

Meningioangiomatosis is a rare disease of the brain. It is characterized by a benign lesion of the leptomeninges usually involving the cerebral cortex, and by leptomeningeal and meningovascular proliferation.^[1] Often the patient will present with seizures. The disease may be either sporadic or associated with neurofibromatosis type 2. The lesion is usually focused in one place, though extremely rare multifocal cases have been reported in both adults and children.^[2] Biopsy is usually necessary for diagnosis. Treatment conventionally involves surgical removal of the lesion.

References

1. Wiebe, S. (1 April 1999). "Meningioangiomatosis: A comprehensive analysis of clinical and laboratory features". Brain. 122 (4): 709–726. doi:10.1093/brain/122.4.709.
2. Jamil O, Ramkissoon S, Folkerth R, Smith E (2012). "Multifocal meningioangiomatosis in a 3-year-old patient". J Neurosurg Pediatrics (Case report). 115 (10): 486–9. doi:10.3171/2012.9.PEDS1224. PMC 3762590. PMID 23020197.

Further reading

• Feng R, Hu J, Che X, Pan L, Wang Z, Zhang M, Huang F, Xu B, Mao R, Sun A, Bao W, Zhong P, Wang Y (2013). "Diagnosis and surgical treatment of sporadic meningioangiomatosis". Clinical Neurology and Neurosurgery. 115: 1407–14. doi:10.1016/j.clineuro.2013.01.021. PMID 23485253.
• Barbosa-Silva E, Dellaretti M, de Carvalho GT, Pereira JL, Botrel L Jr, Pittella JE, de Sousa AA (2012). "Meningioangiomatosis without neurofibromatosis simulating encephalitis in neuroimaging". Surgical Neurology International. 115 (3): 34. doi:10.4103/2152-7806.94035. PMC 3326948. PMID 22530169.
• Drouet A (Dec 2011). "Neurofibromatoses : quel risque épileptique ?" [Seizures in neurofibromatosis. What is the risk?]. Rev Neurol (Paris) (in French). 167 (12): 886–96. doi:10.1016/j.neurol.2011.04.009. PMID 22041820.