Oxotremorine

Oxotremorine
Clinical data
Pregnancy
category
  • C
Routes of
administration
Oral, intravenous
ATC code none
Legal status
Legal status
  • US: Experimental/not yet approved
Identifiers
CAS Number 70-22-4 YesY
IUPHAR/BPS 302
ChemSpider 4469 N
ChEMBL CHEMBL7634 N
ECHA InfoCard 100.000.662
Chemical and physical data
Formula C12H18N2O
Molar mass 206.28
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Oxotremorine is a parasympathomimetic drug that acts as a non-selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

Oxotremorine produces also antipsychotic effects.[3]

References

  1. Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013.
  2. Craig, C. R.; Stitzel, R. E. (2004). Modern Pharmacology. Boston: Little, Brown. p. 149.
  3. http://cat.inist.fr/?aModele=afficheN&cpsidt=20678587

See also


This article is issued from Wikipedia - version of the 9/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.