Picloxydine

Picloxydine

Names
IUPAC name 1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
Identifiers
CAS Number	5636-92-0
3D model (Jmol)	Interactive image
ChEMBL	ChEMBL2104722
ChemSpider	64722
ECHA InfoCard	100.024.623
PubChem	71663
UNII	4YC2PY3AEU
InChI InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) Key: YNCLPFSAZFGQCD-UHFFFAOYAM
SMILES C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
Chemical formula	C20H24Cl2N10
Molar mass	475.37756
Pharmacology
ATC code	S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Picloxydine (trade name Vitabact^[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

References

1. Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Rev Int Trach Pathol Ocul Trop Subtrop Sante Publique. 65 (3–4): 119–32. PMID 3274675.