Primidolol

Primidolol
Names

IUPAC name 1-[2-[[2-Hydroxy-3-(2-methylphenoxy)propyl]amino]ethyl]-5-methylpyrimidine-2,4-dione
Identifiers
CAS Number	67227-55-8
3D model (Jmol)	Interactive image
ChemSpider	61835
KEGG	C11774
PubChem	68563
InChI InChI=1S/C17H23N3O4/c1-12-5-3-4-6-15(12)24-11-14(21)9-18-7-8-20-10-13(2)16(22)19-17(20)23/h3-6,10,14,18,21H,7-9,11H2,1-2H3,(H,19,22,23) Key: RETPFDTUCPKFEC-UHFFFAOYSA-N
SMILES CC1=CC=CC=C1OCC(CNCCN2C=C(C(=O)NC2=O)C)O
Properties
Chemical formula	C₁₇H₂₃N₃O₄
Molar mass	333.39 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Primidolol is a beta adrenergic receptor antagonist.^[1]

Synthesis

J. Augstein, D. A. Cox and A. L. Ham., DE 2238504 (1973). Chem. Abstr. jte, 136325e (1973).

↑ Saltvedt, E; Fauchald, P (1980). "Effect of single and twice daily doses of primidolol (UK-11,443) in hypertension". Current medical research and opinion. 6 (8): 528–33. doi:10.1185/03007998009109482. PMID 6104564.

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