Richard L. Huganir

Richard L. Huganir
Born (1953-03-25) 25 March 1953
Nationality American
Fields Neuroscience
Institutions Johns Hopkins University

Richard L. Huganir (born March 25, 1953) is a Professor and Director of the Solomon H. Snyder Department of Neuroscience,[1] Director of the Kavli Neuroscience Discovery Institute[2] and co-director of the Johns Hopkins Medicine Brain Science Institute at the Johns Hopkins University School of Medicine, as well as an Investigator with the Howard Hughes Medical Institute. He has joint appointments in the Department of Biological Chemistry and the Department of Pharmacology and Molecular Sciences.[3] Huganir is also a member of the Cure Alzheimer's Fund's Research Consortium.

Biography

Dr. Huganir completed his undergraduate work in biochemistry at Vassar College in 1975. He received his Ph.D. degree in biochemistry, molecular and cell biology from Cornell University in 1982 where he performed his thesis research in the laboratory of Dr. Efraim Racker. He was a postdoctoral fellow with the Nobel Laureate, Dr. Paul Greengard, at Yale University School of Medicine from 1982 to 1984. Huganir then moved to the Rockefeller University where he was an Assistant Professor of Molecular and Cellular Neurobiology from 1984-1988.

Huganir moved to the Johns Hopkins University School of Medicine in 1988 as an Associate Investigator in the Howard Hughes Medical Institute and an Associate Professor in the Department of Neuroscience. Huganir became the Director or the Solomon H. Snyder Department of Neuroscience in 2006.

Research

Dr. Huganir’s career has focused on synapses, the connections between nerve cells, in the brain. Dr. Huganir’s general approach has been to study molecular and cellular mechanisms that regulate neurotransmitter receptors. Dr. Huganir’s studies have shown that the regulation of receptor function is a major mechanism for the regulation of neuronal excitability and connectivity in the brain and is critical for many higher brain processes including learning and memory and the proper development of the brain. Moreover, dysregulation of these mechanisms underlie many neurological and psychiatric diseases in several neurological and psychiatric disorders including Alzheimer’s, ALS, schizophrenia, autism, intellectual disability, PTSD as well as in chronic pain and drug addiction.

Huganir has published over 300 papers in peer-reviewed journals.[4]

Honors and Awards

References

  1. ↑ "Faculty profile". Johns Hopkins University School of Medicine. Retrieved 2015-09-30.
  2. ↑ "Kavli Neuroscience Discovery Institute". The Kavli Foundation. Retrieved 2015-10-01.
  3. ↑ Davis, T. H. (2006). "Profile of Richard L. Huganir". Proceedings of the National Academy of Sciences. 103 (12): 4341–4343. doi:10.1073/pnas.0601079103. PMC 1450172Freely accessible. PMID 16537364.
  4. ↑ "Publication List on PubMed". PubMed. Retrieved 2015-09-30.
  5. ↑ "Young Investigator Award". Society for Neuroscience. Retrieved 2015-09-30.
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