S300

S300 may refer to :

• S-300 (missile), a Soviet/Russian surface-to-air missile
• Canon S300, a Canon S Series digital camera
• Sendo S300, a Sendo mobile phone model
• Sony CLIÉ PEG-S300, a Sony CLIÉ PDA model
• HNoMS Ula (S 300), a Royal Norwegian Navy Ula class submarine
• s300/s300j, an engine control unit from Hondata
• Sikorsky S-300, a three-seat helicopter previously produced by Hughes, and later Schweizer, as the 300 series
• The Staudacher S-300 series of stunt airplanes
• The Sephacryl S300 size-exclusion column by GE Healthcare