SH3BP1

SH3BP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4J9D, 4J9F
Identifiers
Aliases	SH3BP1, ARHGAP43, SH3 domain binding protein 1
External IDs	MGI: 104603 HomoloGene: 7534 GeneCards: SH3BP1
Gene ontology Molecular function • SH3 domain binding • protein binding • GTPase activator activity Cellular component • cytoplasm Biological process • positive regulation of GTPase activity • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23616	20401
Ensembl	ENSG00000100092	ENSMUSG00000022436
UniProt	Q9Y3L3	P55194
RefSeq (mRNA)	NM_018957	NM_009164 NM_001316684 NM_001316685 NM_001316686
RefSeq (protein)	NP_061830.3	n/a
Location (UCSC)	Chr 22: 37.63 – 37.67 Mb	Chr 15: 78.9 – 78.92 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

SH3 domain-binding protein 1 is a protein that in humans is encoded by the SH3BP1 gene.^[3][4][5]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
4. Scott MP, Zappacosta F, Kim EY, Annan RS, Miller WT (Jul 2002). "Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1". J Biol Chem. 277 (31): 28238–46. doi:10.1074/jbc.M202783200. PMID 12029088.
5. "Entrez Gene: SH3BP1 SH3-domain binding protein 1".

Further reading

• Cicchetti P, Mayer BJ, Thiel G, Baltimore D (1992). "Identification of a protein that binds to the SH3 region of Abl and is similar to Bcr and GAP-rho". Science. 257 (5071): 803–6. doi:10.1126/science.1379745. PMID 1379745.
• Zhang B, Zheng Y (1998). "Regulation of RhoA GTP hydrolysis by the GTPase-activating proteins p190, p50RhoGAP, Bcr, and 3BP-1". Biochemistry. 37 (15): 5249–57. doi:10.1021/bi9718447. PMID 9548756.
• Västrik I, Eickholt BJ, Walsh FS, et al. (2000). "Sema3A-induced growth-cone collapse is mediated by Rac1 amino acids 17-32". Curr. Biol. 9 (18): 991–8. doi:10.1016/S0960-9822(99)80447-3. PMID 10508610.
• So CW, So CK, Cheung N, et al. (2000). "The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis". Leukemia. 14 (4): 594–601. doi:10.1038/sj.leu.2401692. PMID 10764144.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.