SYTOX

SYTOX (also known as SYTOX Green) is a high-affinity nucleic acid stain developed by biotechnology company Molecular Probes. Because the stain only penetrates cells with compromised plasma membranes, it can be used to investigate antibacterial mechanism of action[1] and confirm loss of bacterial viability.[2][3]

References

  1. ↑ Lee, H.; Woo, E.R.; Lee, D.G. (2015). "Glochidioboside kills pathogenic bacteria by membrane perturbation". Current Microbiology. 71 (1): 1–7. doi:10.1007/s00284-015-0807-9. PMID 25820208.
  2. ↑ Gaforio, J.J.; Serrano, M.J.; Ortega, E.; Algarra, I.; Alvarez de Cienfuegos, G. (2002). "Use of SYTOX green dye in the flow cytometric analysis of bacterial phagocytosis". Cytometry. 48 (2): 93–96. doi:10.1002/cyto.10107. ISSN 0196-4763.
  3. ↑ Lebaron, P.; Catala, P.; Parthuisot, N. (July 1998). "Effectiveness of SYTOX Green Stain for Bacterial Viability Assessment". Applied and Environmental Microbiology. 64 (7): 2697–2700.
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