Tension headache

Tension headache

A woman experiencing a tension headache
Classification and external resources
Specialty Neurology
ICD-10 G44.2
ICD-9-CM 307.81, 339.1
DiseasesDB 12554
MedlinePlus 000797
eMedicine article/1142908
MeSH D018781

Tension headache, also known as tension-type headache, is the most common type of primary headache. The pain can radiate from the lower back of the head, the neck, eyes, or other muscle groups in the body typically affecting both sides of the head. Tension-type headaches account for nearly 90% of all headaches.

Tricyclic antidepressants appear to be useful for prevention.[1] Evidence is poor for SSRIs, propranolol and muscle relaxants.[2][3] For the treatment of a tension headache, ibuprofen is effective.[4]

As of 2013 tension headaches affect about 1.6 billion people (20.8% of the population)[5] and are more common in women than men (23% to 18% respectively).[6]

Signs and symptoms

Tension-type headache pain is often described as a constant pressure, as if the head were being squeezed in a vise. The pain is frequently present on both sides of the head at the same time. Tension-type headache pain is typically mild to moderate, but may be severe.

Frequency and duration

Tension-type headaches can be episodic or chronic.[7] Episodic tension-type headaches are defined as tension-type headaches occurring fewer than 15 days a month, whereas chronic tension headaches occur 15 days or more a month for at least 6 months. Tension-type headaches can last from minutes to days, months or even years, though a typical tension headache lasts 4–6 hours.

Cause

Various precipitating factors may cause tension-type headaches in susceptible individuals:[8]

Tension-type headaches may be caused by muscle tension around the head and neck. One of the theories says that the main cause for tension-type headaches and migraine is teeth clenching which causes a chronic contraction of the temporalis muscle.

Another theory is that the pain may be caused by a malfunctioning pain filter which is located in the brain stem. The view is that the brain misinterprets information—for example from the temporal muscle or other muscles—and interprets this signal as pain. One of the main neurotransmitters that is probably involved is serotonin. Evidence for this theory comes from the fact that chronic tension-type headaches may be successfully treated with certain antidepressants such as amitriptyline. However, the analgesic effect of amitriptyline in chronic tension-type headache is not solely due to serotonin reuptake inhibition, and likely other mechanisms are involved. Recent studies of nitric oxide (NO) mechanisms suggest that NO may play a key role in the pathophysiology of CTTH.[9] The sensitization of pain pathways may be caused by or associated with activation of nitric oxide synthase (NOS) and the generation of NO. Patients with chronic tension-type headache have increased muscle and skin pain sensitivity, demonstrated by low mechanical, thermal and electrical pain thresholds. Hyperexcitability of central nociceptive neurons (in trigeminal spinal nucleus, thalamus, and cerebral cortex) is believed to be involved in the pathophysiology of chronic tension-type headache.[10] Recent evidence for generalized increased pain sensitivity or hyperalgesia in CTTH strongly suggests that pain processing in the central nervous system is abnormal in this primary headache disorder. Moreover, a dysfunction in pain inhibitory systems may also play a role in the pathophysiology of chronic tension-type headache.[11]

If other treatment is not working, a health care provider may use an MRI to confirm a more complicated diagnosis.[12]

Prevention

Lifestyle

Drinking water and avoiding dehydration helps in preventing tension headache.[12] Using stress management and relaxing often makes headaches less likely.[12] Drinking alcohol can make headaches more likely or severe.[12] Good posture might prevent headaches if there is neck pain.[12] People who have jaw clenching might develop headaches, and getting treatment from a dentist might prevent those headaches.[12] Biofeedback techniques may also help.[13][14]

Medications

People who have 15 or more headaches in a month may be treated with certain types of daily antidepressants which act to prevent continued tension headaches from occurring.[12] In those who are predisposed to tension type headaches the first-line preventative treatment is amitriptyline, whereas mirtazapine and venlafaxine are second-line treatment options.[15] Tricyclic antidepressants have been found to be more effective than SSRIs but have greater side effects.[1] Evidence is insufficient for the use of SSRIs, propranolol and muscle relaxants for prevention of tension headaches.[2][3]

Treatment

Treatment for a current tension headache is to drink water and confirm that there is no dehydration.[12] If symptoms do not resolve within an hour for a person who has had water, then stress reduction might resolve the issue.[12]

Medications

Over-the-counter drugs, like acetaminophen or ibuprofen, are only helpful as a treatment for a few times in a week at most.[12] Analgesic/sedative combinations are widely used (e.g., analgesic/antihistamine combinations like Syndol, Mersyndol and Percogesic, analgesic/barbiturate combinations such as Fiorinal). Frequent use of analgesics may, however, lead to medication overuse headache.[15]

Botulinum toxin does not appear to be helpful.[16]

Manual therapy

Though evidence for acupuncture is slight, some suggest it may be useful in those with frequent or chronic tension headaches.[17]

People with tension-type headache often use spinal manipulation, soft tissue therapy, and myofascial trigger point treatment. Studies of effectiveness are mixed. A 2006 systematic review found no rigorous evidence supporting manual therapies for tension headache.[18] A 2005 structured review found only weak evidence for the effectiveness of chiropractic manipulation for tension headache, and that it was probably more effective for tension headache than for migraine.[19] A 2004 Cochrane review found that spinal manipulation may be effective for migraine and tension headache, and that spinal manipulation and neck exercises may be effective for cervicogenic headache.[20] Two other systematic reviews published between 2000 and May 2005 did not find conclusive evidence in favor of spinal manipulation.[21] A 2012 systematic review of manual therapy found that hands-on work may reduce both the frequency and the intensity of chronic tension-type headaches.[22]

Epidemiology

Tension headaches affect about 1.4 billion people (20.8% of the population) and are more common in women than men (23% to 18% respectively).[6] Despite its benign character, tension-type headache, especially in its chronic form, can impart significant disability on patients as well as burden on society at large.[23]

Prognosis

Tension headaches that do not occur as a symptom of another condition may be painful, but are not harmful. It is usually possible to receive relief through treatment. Tension headaches that occur as a symptom of another condition are usually relieved when the underlying condition is treated. Frequent use of pain medications in patients with tension-type headache may lead to the development of medication overuse headache or rebound headache.

References

  1. 1 2 Jackson JL, Shimeall W, Sessums L, et al. (2010). "Tricyclic antidepressants and headaches: systematic review and meta-analysis". BMJ. 341: c5222. doi:10.1136/bmj.c5222. PMC 2958257Freely accessible. PMID 20961988.
  2. 1 2 Verhagen AP, Damen L, Berger MY, Passchier J, Koes BW (April 2010). "Lack of benefit for prophylactic drugs of tension-type headache in adults: a systematic review". Fam Pract. 27 (2): 151–65. doi:10.1093/fampra/cmp089. PMID 20028727.
  3. 1 2 Banzi, R; Cusi, C; Randazzo, C; Sterzi, R; Tedesco, D; Moja, L (1 May 2015). "Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) for the prevention of tension-type headache in adults.". The Cochrane database of systematic reviews. 5: CD011681. doi:10.1002/14651858.CD011681. PMID 25931277.
  4. ↑ Derry, S; Wiffen, PJ; Moore, RA; Bendtsen, L (31 July 2015). "Ibuprofen for acute treatment of episodic tension-type headache in adults.". The Cochrane database of systematic reviews. 7: CD011474. doi:10.1002/14651858.CD011474.pub2. PMID 26230487.
  5. ↑ Global Burden of Disease Study 2013, Collaborators (22 August 2015). "Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.". Lancet (London, England). 386 (9995): 743–800. doi:10.1016/s0140-6736(15)60692-4. PMID 26063472.
  6. 1 2 Vos, T; Flaxman, A. D.; Naghavi, M; Lozano, R; Michaud, C; Ezzati, M; Shibuya, K; Salomon, J. A.; Abdalla, S; Aboyans, V; Abraham, J; Ackerman, I; Aggarwal, R; Ahn, S. Y.; Ali, M. K.; Alvarado, M; Anderson, H. R.; Anderson, L. M.; Andrews, K. G.; Atkinson, C; Baddour, L. M.; Bahalim, A. N.; Barker-Collo, S; Barrero, L. H.; Bartels, D. H.; Basáñez, M. G.; Baxter, A; Bell, M. L.; Benjamin, E. J.; et al. (Dec 15, 2012). "Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010". Lancet. 380 (9859): 2163–96. doi:10.1016/S0140-6736(12)61729-2. PMID 23245607.
  7. ↑ Headache Classification Subcommittee of the International Headache Society (2004). "The International Classification of Headache Disorders: 2nd edition". Cephalalgia. 24 (Suppl 1): 9–160. doi:10.1111/j.1468-2982.2004.00653.x. PMID 14979299. as PDF
  8. ↑ Muscle Contraction Tension Headache at eMedicine
  9. ↑ Ashina M, Lassen LH, Bendtsen L, Jensen R, Olesen J; Lassen; Bendtsen; Jensen; Olesen (January 1999). "Effect of inhibition of nitric oxide synthase on chronic tension-type headache: a randomised crossover trial". Lancet. 353 (9149): 287–9. doi:10.1016/S0140-6736(98)01079-4. PMID 9929022.
  10. ↑ Ashina S, Bendtsen L, Ashina M; Bendtsen; Ashina (December 2005). "Pathophysiology of tension-type headache". Curr Pain Headache Rep. 9 (6): 415–22. doi:10.1007/s11916-005-0021-8. PMID 16282042.
  11. ↑ Pielsticker A, Haag G, Zaudig M, Lautenbacher S; Haag; Zaudig; Lautenbacher (November 2005). "Impairment of pain inhibition in chronic tension-type headache". Pain. 118 (1–2): 215–23. doi:10.1016/j.pain.2005.08.019. PMID 16202520.
  12. 1 2 3 4 5 6 7 8 9 10 Consumer Reports (28 April 2016). "Tension Headache Treatment and Prevention". Consumer Reports. Retrieved 25 May 2016.
  13. ↑ Nestoriuc Y, Rief W, Martin A; Rief; Martin (June 2008). "Meta-analysis of biofeedback for tension-type headache: efficacy, specificity, and treatment moderators". J Consult Clin Psychol. 76 (3): 379–96. doi:10.1037/0022-006X.76.3.379. PMID 18540732.
  14. ↑ Rains JC (May 2008). "Change mechanisms in EMG biofeedback training: cognitive changes underlying improvements in tension headache". Headache. 48 (5): 735–6; discussion 736–7. doi:10.1111/j.1526-4610.2008.01119_1.x. PMID 18471128.
  15. 1 2 Bendtsen L, Jensen R; Jensen (May 2011). "Treating tension-type headache — an expert opinion". Expert Opin Pharmacother. 12 (7): 1099–109. doi:10.1517/14656566.2011.548806. PMID 21247362.
  16. ↑ Simpson, D. M.; Hallett, M.; Ashman, E. J.; Comella, C. L.; Green, M. W.; Gronseth, G. S.; Armstrong, M. J.; Gloss, D.; Potrebic, S.; Jankovic, J.; Karp, B. P.; Naumann, M.; So, Y. T.; Yablon, S. A. (18 April 2016). "Practice guideline update summary: Botulinum neurotoxin for the treatment of blepharospasm, cervical dystonia, adult spasticity, and headache: Report of the Guideline Development Subcommittee of the American Academy of Neurology". Neurology. 86: 1818–1826. doi:10.1212/WNL.0000000000002560.
  17. ↑ Linde K, Allais G, Brinkhaus B, Manheimer E, Vickers A, White AR; Allais; Brinkhaus; Manheimer; Vickers; White (2009). "Acupuncture for tension-type headache". Cochrane Database Syst Rev. 1 (1): CD007587. doi:10.1002/14651858.CD007587. PMC 3099266Freely accessible. PMID 19160338.
  18. ↑ Fernández-de-las-Peñas C, Alonso-Blanco C, Cuadrado ML, Miangolarra JC, Barriga FJ, Pareja JA; Alonso-Blanco; Cuadrado; Miangolarra; Barriga; Pareja (2006). "Are manual therapies effective in reducing pain from tension-type headache?: a systematic review". Clin J Pain. 22 (3): 278–85. doi:10.1097/01.ajp.0000173017.64741.86. PMID 16514329.
  19. ↑ Biondi DM (2005). "Physical treatments for headache: a structured review". Headache. 45 (6): 738–46. doi:10.1111/j.1526-4610.2005.05141.x. PMID 15953306.
  20. ↑ Bronfort G, Nilsson N, Haas M; et al. (2004). Brønfort, Gert, ed. "Cochrane Database of Systematic Reviews". Cochrane Database Syst Rev (3): CD001878. doi:10.1002/14651858.CD001878.pub2. PMID 15266458. |chapter= ignored (help)
  21. ↑ Ernst E, Canter PH; Canter (2006). "A systematic review of systematic reviews of spinal manipulation". J R Soc Med. 99 (4): 192–6. doi:10.1258/jrsm.99.4.192. PMC 1420782Freely accessible. PMID 16574972.
  22. ↑ Chaibi, A; Russell, MB (July 2012). "Manual therapies for cervicogenic headache: a systematic review.". The journal of headache and pain. 13 (5): 351–9. doi:10.1007/s10194-012-0436-7. PMID 22460941.
  23. ↑ Lenaerts, M. E. (2006). "Burden of tension-type headache". Current pain and headache reports. 10 (6): 459–62. doi:10.1007/s11916-006-0078-z. PMID 17087872.

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