Toroku arsenic disease

Toroku arsenic disease (土呂久砒素公害 Toroku hiso kōgai) was a disease resulting from air and water pollution from a refinery at a mine at Toroku, located in Takachiho, Nishiusuki District, Miyazaki, Japan.

It emitted arsenic-containing air, resulting in patients with chronic arsenic poisoning producing skin changes, skin cancers and sometimes lung cancer. The Sumitomo Metal Mining Co., Ltd., which bought the right of mining was sued by the patients for health damage, but 15 years later, the lawsuit ended with a compromise.

History

The pollution at Toroku dates back to 1690 according to A Table of Public Hazards of Japan[1]

Medical examinations

Seven patients were examined extensively at Kumamoto University, and they were diagnosed as having chronic arsenic poisoning due to pollution, in a report published in 1973.[2] The same team increased the number of patients to 48 in 1976, while Hotta and his co-workers made extensive studies of the pollution.[3]

Symptoms of patients in Toroku pollution

Skin and otorhinolaryngological symptoms

Nakamura et al. characterized the condition by pigmentation which is either macular or diffuse, appearing both in covered and exposed areas. Punctate depigmentation appears in raindrop shapes, and hard keratoses are either localized or diffuse. Malignant changes may occur. They pointed out nasal septum defects. The environmental agency first indicated the skin and ENT findings of nasal scar or septum defect as necessary symptoms for the Toroku Pollution.

Other symptoms

In addition to the skin and ENT findings, neuritis was added as a criterion of chronic arsenic poisoning. Bowen's disease, Lung cancer, and cancer of the urinary organ were added as appearing following chronic arsenic poisoning.

Arsenic pollution in other areas of Japan

References

  • Arsenic pollution A global problem
  • Nakamura I et al. "Chronic arsenical poisoning due to environmental pollution. Seven cases among inhabitants near an abandoned mine." (1976). Kumamoto Med J. 29, 172-186.
  • Hotta N. et al. "Clinical aspects of chronic arsenic poisoning due to environmental and occupational pollution in and around a small refining spot." (1989). Nihon Taishitsugaku Zasshi, 53,49-70.
  1. Chronological Table of Public Hazards and Occupational Disease(1977), edited by Iijima N. Kouga Taisaku Gijutu Douyuukai, Tokyo
  2. Nakamura I et al. "Chronic arsenic poisoning, Cases around Toroku mine".(1973) Report 1 and Report 2. J Kumamoto Med Soc. 47,486-515,516-530.
  3. Hotta et al. "Clinical studies on Toroku pollution disease." (1979) Taishitsu Igaku enkyusho Houkoku 29,199-235.
  4. Hotta, N. Chigaku kyoiku to Kagaku Undo. "Geographical Conditions of Arsenic Pollution." (1997), Tokubetsugo, 14-27.
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