Walter Bodmer

Sir Walter Bodmer
Born	Walter Fred Bodmer (1936-01-10) 10 January 1936^[1]
Institutions	Stanford University University of Oxford
Alma mater	University of Cambridge (BA, PhD)
Thesis	The study of population genetics and gene effects, with special reference to Primula vulgaris and the house mouse (1959)
Academic advisors	Ronald Fisher^[2]
Doctoral students	Marcus Feldman^[2]^[3] Shaan-Chirag Gandhi^[4] Matthew Johnson^[5] Matthew Jones^[6] Ruchi Patel^[7]
Influenced	Tomas Lindahl^[8]
Notable awards	Royal Medal (2013) Michael Faraday Prize (1994) Ellison–Cliffe Lecture (1987) William Allan Award (1980)^[9] FRS (1974)
Spouse	Julia Bodmer (m. 1956; d. 2001)
Website www.imm.ox.ac.uk/walter-bodmer-2 www.oncology.ox.ac.uk/research/walter-bodmer

Sir Walter Fred Bodmer FRS (born 10 January 1936^[10] in Frankfurt am Main, Germany^[11]) is a German-born British human geneticist.^[12]^[13]^[14]^[15]^[16]^[17]^[18]

Education

Bodmer was educated at Manchester Grammar School and went on to study the Mathematical Tripos at the University of Cambridge as a student of Clare College, Cambridge. He was awarded his PhD in 1959 from Cambridge for research on population genetics in the house mouse and Primula vulgaris (primrose) supervised by Ronald Fisher.^[2]

Career and research

In 1961 Bodmer joined Joshua Lederberg's laboratory in the Genetics Department of Stanford University as a postdoctoral researcher, continuing his work on population genetics.^[19] In 1962 Walter Bodmer was appointed to the faculty at Stanford. He left Stanford University in 1970 to become the first Professor of Genetics at the University of Oxford .^[20]

Bodmer developed models for population genetics and worked on the human leukocyte antigen system and the use of somatic cell hybrids for human linkage studies. In 1985 he chaired a Royal Society committee which wrote The Bodmer Report; this has been credited with starting the movement for the public understanding of science.^[21]

Bodmer was one of the first to suggest the idea of the Human Genome Project.^[22] In 1987 he received the Ellison-Cliffe Medal from the Royal Society of Medicine. He was the director of research (1979–1991) and then Director General (1991–1996) of the Imperial Cancer Research Fund. He was also Chancellor of the University of Salford, England (1995–2005; succeeded by Sir Martin Harris) and Principal of Hertford College, Oxford (1996–2005; succeeded by Dr. John Landers).

In 2005, Bodmer was appointed to lead a £2.3 million project (roughly 4.5 million USD) by the Wellcome Trust at University of Oxford to examine the genetic makeup of the United Kingdom - the People of the British Isles project. He was joined by Oxford Professor Peter Donnelly (a population genetics and statistics expert) and the Wellcome Trust Principal Research Fellow Lon Cardon. Bodmer said "Our aim is to characterise the genetic make-up of the British population and relate this to the historical and archaeological evidence." The researchers presented some of their findings to the public via the Channel 4 television series "Faces of Britain." On 14 April 2007, Channel 4 in Britain aired a program that highlighted the study’s then-current findings. The project took DNA samples from hundreds of volunteers throughout Britain, seeking tell-tale fragments of DNA that would reveal the biological traces of successive waves of colonisers — Celts, Saxons, Vikings, etc. — in various parts of Britain. The findings showed that the Viking invasion of Britain was predominantly from Danish Vikings while the Orkney Islands were settled by Norwegian Vikings.

He is currently Head of the Cancer and Immunogenetics Laboratory in the Weatherall Institute of Molecular Medicine at the University of Oxford. Research interests of the laboratory include the fundamental genetics and biology of colorectal cancer.

Honours and awards

Bodmer has won numerous awards including:

1974: Fellow of the Royal Society ^[23]^[24]
1980: William Allan Award
1986: Knighted
1987: Ellison-Cliffe Medal from the Royal Society of Medicine.
1988: Honorary Degree (Doctor of Science) from the University of Bath.^[25]
1994: Michael Faraday Prize
2013: Royal Medal from the Royal Society
1984: delivered the Royal Institution Christmas Lecture on The Message of the Genes.

His certificate of election to the Royal Society reads:

“

Distinguished for his theoretical and experimental contributions to genetics. His analyses of population genetics models, especially human, his contribution to the understanding of bacterial transformation, to the understanding of the HL-A system, and to the use of somatic cell hybrids for human linkage studies are outstanding. Few scientists have contributed distinguished work in such a range of fields, and involving such a range of experience of techniques, mathematical and experimental, and such a range of organisms.^[23]

”

Personal life

Bodmer's father was Jewish so the family were obliged to leave Germany in 1938 and settled in Manchester. In 1956 Bodmer married Julia Bodmer (née Pilkington) 1934 – 2001 a British geneticist. They had three children.^[1]

References

1 2 BODMER, Prof. Walter. Who's Who. 2015 (online Oxford University Press ed.). A & C Black, an imprint of Bloomsbury Publishing plc. (subscription required)
1 2 3 Walter Bodmer at the Mathematics Genealogy Project
↑ Feldman, Marcus (1979). Some topics in theoretical population genetics (PhD thesis). Stanford University. OCLC 651748270.
↑ Gandhi, Shaan-Chirag Chandrahas (2010). Regulation of stemness and differentiation in colorectal cancer (DPhil thesis). University of Oxford.
↑ Johnston, Matthew David (2008). Mathematical modelling of cell population dynamics in the colonic crypt with application to colorectal cancer (DPhil thesis). University of Oxford.
↑ Jones, Matthew (2014). MiR-215 regulates differentiation in colorectal cancer stem cells (DPhil thesis). University of Oxford.
↑ Patel, Ruchi (2014). The role of homeobox gene NKX3.1 in prostate cancer (DPhil thesis). University of Oxford.
↑ http://libgallery.cshl.edu/items/show/32050
↑ Cavalli-Sforza, L. L. (1981). "The William Allan Memorial Award: Presented to Walter F. Bodmer, PhD, at the annual meeting of the American Society of Human Genetics New York, September 24-27, 1980". American Journal of Human Genetics. 33 (5): 659–63. PMC 1685126. PMID 7027789.
↑ The Times 10 January 2009, Retrieved 2010-01-09 (subscription required)
↑ "BSI HONORARY MEMBER: Sir Walter Bodmer". British Society of Immunology. Archived from the original on 2015-04-02.
↑ Leslie, S; Winney, B; Hellenthal, G; Davison, D; Boumertit, A; Day, T; Hutnik, K; Royrvik, E. C.; Cunliffe, B; Wellcome Trust Case Control Consortium 2; International Multiple Sclerosis Genetics Consortium; Lawson, D. J.; Falush, D; Freeman, C; Pirinen, M; Myers, S; Robinson, M; Donnelly, P; Bodmer, W (2015). "The fine-scale genetic structure of the British population". Nature. 519 (7543): 309–14. doi:10.1038/nature14230. PMID 25788095.
↑ Rodrigues, N. R.; Rowan, A; Smith, M. E.; Kerr, I. B.; Bodmer, W. F.; Gannon, J. V.; Lane, D. P. (1990). "P53 mutations in colorectal cancer". Proceedings of the National Academy of Sciences of the United States of America. 87 (19): 7555–9. doi:10.1073/pnas.87.19.7555. PMC 54786. PMID 1699228.
↑ "Prof Sir Walter Bodmer FRS, Weatherhall Institute for Molecular Medicine". University of Oxford. Archived from the original on April 17, 2015.
↑ "Walter Bodmer: Cancer and Immunogenetics Laboratory". University of Oxford. Archived from the original on 2015-03-04.
↑ Hemminki, A.; Markie, D.; Tomlinson, I.; Avizienyte, E.; Roth, S.; Loukola, A.; Bignell, G.; Warren, W.; Aminoff, M.; Höglund, P.; Järvinen, H.; Kristo, P.; Pelin, K.; Ridanpää, M.; Salovaara, R.; Toro, T.; Bodmer, W.; Olschwang, S.; Olsen, A. S.; Stratton, M. R.; de la Chapelle, A.; Aaltonen, L. A. (1998). "A serine/threonine kinase gene defective in Peutz-Jeghers syndrome.". Nature. 391 (6663): 184–7. doi:10.1038/34432. PMID 9428765.
↑ Bodmer, W; Bonilla, C (2008). "Common and rare variants in multifactorial susceptibility to common diseases". Nature Genetics. 40 (6): 695–701. doi:10.1038/ng.f.136. PMC 2527050. PMID 18509313.
↑ Walter Bodmer's publications indexed by the Scopus bibliographic database, a service provided by Elsevier. (subscription required)
↑ "Early Computers at Stanford". Stanford University. Archived from the original on 2014-08-13.
↑ Conversation with Walter Bodmer, San Francisco, 4 Dec.2010
↑ "Public Understanding of Science, 1985". Royal Society. Archived from the original on 2013-10-19.
↑ "HUGO presidents". Archived from the original on 2015-04-08.
1 2 "EC/1974/01: Bodmer, Walter Fred". London: The Royal Society. Archived from the original on 2015-04-11.
↑ "Sir Walter Bodmer FMedSci FRS". London: Royal Society. Archived from the original on 2015-10-09.
↑ "Honorary Graduates 1989 to present". bath.ac.uk. University of Bath. Retrieved 18 February 2012.

External links

Academic offices
Preceded by The Duchess of York	Chancellor of the University of Salford 1995–2005	Succeeded by Sir Martin Harris
Preceded by Christopher Zeeman	Principal of Hertford College, Oxford 1996–2005	Succeeded by John Landers

Presidents of the Royal Statistical Society

19th century	1834–1836 The Marquess of Lansdowne 1836–1838 Sir Charles Lemon, Bt 1838–1840 The Earl FitzWilliam 1840–1842 Viscount Sandon 1842–1843 The Marquess of Lansdowne 1843–1845 Lord Ashley 1845–1847 The Lord Monteagle of Brandon 1847–1849 The Earl FitzWilliam 1849–1851 The Earl of Harrowby 1851–1853 The Lord Overstone 1853–1855 The Earl FitzWilliam 1855–1857 The Earl of Harrowby 1857–1859 Lord Stanley 1859–1861 Lord John Russell 1861–1863 Sir John Pakington, Bt 1863–1865 William Henry Sykes 1865–1867 The Lord Houghton 1867–1869 William Ewart Gladstone 1869–1871 William Newmarch 1871–1873 William Farr 1873–1875 William Guy 1875–1877 James Heywood 1877–1879 George Shaw-Lefevre 1879–1880 Thomas Brassey 1880–1882 James Caird 1882–1884 Robert Giffen 1884–1886 Rawson W. Rawson 1886–1888 George Goschen 1888–1890 Thomas Graham Balfour 1890–1892 Frederic J. Mouat 1892–1894 Charles Booth 1894–1896 The Lord Farrer 1896–1897 John Biddulph Martin 1897 Alfred Edmund Bateman 1897–1899 Leonard Courtney 1899–1900 Henry Fowler 1900–1902 The Lord Avebury

20th century	1902–1904 Patrick George Craigie 1904–1905 Sir Francis Powell, Bt 1905–1906 The Earl of Onslow 1906–1907 Richard Martin 1907–1909 Sir Charles Dilke, Bt 1909–1910 Jervoise Athelstane Baines 1910–1912 Lord George Hamilton 1912–1914 Francis Ysidro Edgeworth 1914–1915 The Lord Welby 1915–1916 Lord George Hamilton 1916–1918 Bernard Mallet, Registrar General 1918–1920 Herbert Samuel 1920–1922 R. Henry Rew 1922–1924 The Lord Emmott 1924–1926 Udny Yule 1926–1928 The Viscount D'Abernon 1928–1930 A. William Flux 1930–1932 Sir Josiah Stamp 1932–1934 The Lord Meston 1934–1936 Major Greenwood 1936–1938 The Lord Kennet 1938–1940 Arthur Lyon Bowley 1940–1941 Henry William Macrosty 1941 Hector Leak 1941–1943 William Beveridge 1943–1945 Charles Ernest Snow 1945–1947 The Lord Woolton 1947–1949 David Heron 1949–1950 Sir Geoffrey Heyworth 1950–1952 Austin Bradford Hill 1952–1954 Ronald Fisher 1954–1955 The Lord Piercy 1955–1957 Egon Pearson 1957–1959 Harry Campion 1959–1960 Hugh Beaver 1960–1962 Maurice Kendall 1962–1964 Joseph Oscar Irwin 1964–1965 Sir Paul Chambers 1965–1966 L. H. C. Tippett 1966–1967 M. S. Bartlett 1967–1968 Frank Yates 1968–1969 Arthur Cockfield 1969–1970 R. G. D. Allen 1970–1971 Bernard Benjamin 1971–1972 George Alfred Barnard 1972–1973 Harold Wilson 1973–1974 D. J. Finney 1974–1975 Henry Daniels 1975–1977 Stella Cunliffe 1977–1978 Henry Wynn 1978–1980 Sir Claus Moser 1980–1982 David Cox 1982–1984 Peter Armitage 1984–1985 Walter Bodmer 1985–1986 John Nelder 1986–1987 James Durbin 1987–1989 John Kingman 1989–1991 Peter G. Moore 1991–1993 T. M. F. Smith 1993–1995 D. J. Bartholomew 1995–1997 Adrian Smith 1997–1999 R. N. Curnow 1999–2001 Denise Lievesley

21st century	2001–2003 Peter Green 2003–2005 Andy Grieve 2005–2007 Tim Holt 2008–2009 David Hand 2010–2010 Bernard Silverman (resigned Feb 2010; replaced pro tem by David Hand) 2011–2012 Valerie Isham 2013–John Pullinger

Category List

Authority control	WorldCat Identities VIAF: 97686522 LCCN: n83044366 ISNI: 0000 0001 0927 8138 ORCID: 0000-0001-6244-9792 GND: 174099118 SUDOC: 083157352 BNF: cb12455852t (data) MGP: 138924

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