William Lowe
William Lowe may refer to:
- William Lowe (cricketer) (1873–1945), English cricketer
- William Drury Lowe (1802–1877), English landowner and High Sheriff of Derbyshire
- William Lowe (British Army officer) (1861–1944)
- William Lowe (athlete) (born 1901), Irish sprinter
- William C. Lowe (1941–2013), IBM Executive and "Father of the IBM PC"
- William M. Lowe (1842–1882), American politician in Alabama
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