Xeroderma

Xerosis
The surface of the knuckles of a hand with xeroderma
Classification and external resources
Specialty endocrinology, ophthalmology, dermatology
ICD-10 E50.0-E50.3, H11.1, L85.3
ICD-9-CM 264.0-264.3, 372.53, 706.8
DiseasesDB 32733
MedlinePlus 000835

Xeroderma or xerodermia (also known as xerosis cutis[1]), derived from the Greek words for "dry skin", is a condition involving the integumentary system, which in most cases can safely be treated with emollients or moisturizers. Xeroderma occurs most commonly on the scalp, lower legs, arms, hands, the knuckles, the sides of the abdomen, and thighs. Symptoms most associated with xeroderma are scaling (the visible peeling of the outer skin layer), itching, and skin cracking.[2]

Common causes

Xeroderma is a very common condition. It happens more often in the winter where the cold air outside and the hot air inside creates a low relative humidity. This causes the skin to lose moisture and it may crack and peel. Bathing or hand washing too frequently, especially if one is using harsh soaps, can contribute to xeroderma. Xeroderma can be caused by a deficiency of vitamin A, vitamin D, systemic illness, severe sunburn, or some medication.[3] Xeroderma can be caused by choline inhibitors. Detergents such as washing powder and dishwashing liquid can cause xeroderma.

Prevention

Today, many creams and lotions, commonly based on vegetable oils/butters, petroleum oils/jellies, and even lanolin[4] are widely available. As a preventive measure, such products may be rubbed onto the affected area as needed (often every other day) to prevent dry skin. The skin is then patted dry to prevent removal of natural lipids from the skin.[5]

Cure

Repeated application (typically over a few days) of emollients or skin lotions/creams to the affected area will likely result in quick alleviation of xeroderma. In particular, application of highly occlusive barriers to moisture, such as petrolatum, vegetable oils/butters, and mineral oil have been shown to provide excellent results. Many individuals find specific commercial skin creams and lotions (often comprising oils, butters, and or waxes emulsified in water) quite effective (although individual preferences and results vary among the wide array of commercially available creams). Lanolin, a natural mixture of lipids derived from sheep's wool, helps replace natural lipids in human skin and has been used since ancient times (and in modern medicine) as among the most powerful treatments for xeroderma. However, lanolin is a common allergen. Also, pure lanolin is a thick waxy substance which, for many individuals, proves difficult and inconvenient for general use on dry skin (especially over large areas of the body). As a result, many formulated lanolin products, having a softer consistency than pure lanolin, are available.

Safety

Many skin creams include common allergens such as fragrances, parabens, and lanolin.[6]

Effects of Xeroderma on the hand

See also

References

  1. ↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  2. ↑ Information and introductory article on wrongdianosis.com. Retrieved from http://www.wrongdiagnosis.com/x/xeroderma/intro.htm.[]
  3. ↑ Entry on medterms.com
  4. ↑ Overview of Lanolin Basics at www.lanicare.com/lanolin.html
  5. ↑ Lee, Doctor. "Dry Skin Prevention". Retrieved 18 August 2011.
  6. ↑ Zirwas MJ, Stechschulte SA (2008). "Moisturizer allergy: diagnosis and management". The Journal of Clinical and Aesthetic Dermatology. 1 (4): 38–44. PMC 3016930Freely accessible. PMID 21212847.
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