- Giannis Agouris, Greek writer and journalist
- Ioannis Amanatidis, Greek footballer
- Yannis Anastasiou, Greek footballer
- Yiannis Andrianopoulos, Greek footballer
- Giannis Antetokounmpo, Greek basketball player
- Giannis Apostolidis, Greek footballer
- Yiannis Arabatzis, Greek goalkeeper
- Yannis Bakos, economist
- Ioannis Banias (1939–2012), Greek politician
- Yannis Behrakis, Greek photojournalist
- Yiannis Bourousis, Greek basketball player
- Yannis Brown, composer
- Yiannis Carras, Greek shipping magnate
- Giannis Chondrogiannis, Greek politician
- Jani Christou, Greek composer
- Giannis Chrysafis, Greek footballer
- Ioannis Damanakis, Greek footballer
- Giannis Dragasakis, Greek politician
- Yiannis Dritsas, the inventor of Greek instant frappé
- Yiannis Eitziridis, Greek musician
- Giannis Fysekis, Greek footballer
- Giannis Gagaloudis, Greek basketball player
- Giannis Galitsios, Greek footballer
- Giannis Georgallis, Greek basketball player
- Giannis Giannoulis, Greek-Canadian basketball player
- Giannis Gionakis, Greek actor
- Yannis Goumas, Greek footballer
- Ioannis Gounaris, Greek footballer
- Yiannis Grivas, Greek judge
- Yannis Hotzeas, Greek communist thinker
- Yanni (Yiánnis Hryssomállis), Greek composer, keyboardist
- Giannis Iliopoulos, Greek basketball player
- Giannis Ioannidis, Greek basketball coach and politician
- Giannis Kalambokis, Greek basketball player
- Ioannis Kalitzakis, Greek footballer
- Giannis Katemis, Greek footballer
- Yannis Kondos, Greek poet
- Yannis Kontos, Greek photojournalist
- Yiannis Koskiniatis, Greek footballer
- Yiannis Kouros, Greek marathon runner
- Ioannis Kyrastas, Greek footballer and football manager
- Giannis Kyriakopoulos, Greek basketball player
- Yiannis Latsis, Greek shipping tycoon
- Giannis Liourdis, Greek footballer
- Yannis Makriyannis, Greek General
- Yannis Manakis, Greek photographer
- Giannis Maniatis, Greek footballer
- Yannis Margaritis, Greek theater director
- Giannis Markopoulos, Greek composer
- Giannis Mihalopoulos, Greek actor
- Giannis Milonas, Greek basketball player
- Yiannis Moralis, Greek artist
- Yiannis N. Moschovakis, Greek theorist
- Yiannis Okkas, Cypriot footballer
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- Yiannis Papadopoulos, Greek footballer
- Yiannis Papaioannou, Greek composer
- Yannis Papathanasiou, Greek politician
- Yiannis Parios, Greek singer
- Giannis Pasas, Greek footballer
- Yiannis Patilis, Greek poet
- Yannis Pathiakakis Stadium, Greek stadium
- Giannis Pechlivanis, Greek footballer
- Yiannis Pharmakis, Greek leader
- Yannis Philippakis, Guitarist and lead singer of Foals
- Giannis Ploutarhos, Greek singer
- Yiannis Poulakas, Greek painter and stage designer
- Giannis Poulopoulos, Greek singer
- Yannis Psycharis, Greek author and philologist
- Yiannis Psychopedis, Greek art movement
- Yiannis Ritsos, Greek poet
- Yannis Salibur, French footballer
- Ioannis Samaras, Greek footballer
- Giannis Sampson, Cypriot footballer
- Giannis Sfakianakis, Greek footballer
- Giannis Sioutis, Greek basketball player
- Yiannis Skarimbas, Greek writer
- Giannis Skopelitis, Greek footballer
- Yannis Smaragdis, Greek film director
- Giannis Sotirhos, Greek footballer
- Yiannis Spyropoulos, Greek painter
- Yannis Stavrou, Greek painter
- Yannis Tafer, French footballer
- Yannis Tamtakos, Greek political activist
- Giannis Taralidis, Greek footballer
- Yianis Tomaras, Greek footballer
- Yiannis Tridimas, Greek long-distance runner
- Yannis Tsarouchis, Greek painter
- Giannis Tsimitselis, Greek actor
- Giannis Valaoras, Greek footballer
- Giannis Valinakis, Greek politician
- Giannis Vardinogiannis, Greek businessman
- Yanis Varoufakis, Greek economist
- Yannis Varveris, Greek poet
- Giannis Vogiatzis, Greek actor
- Iannis Xenakis, Greek composer
- Yiannis Xipolitas, Cypriot footballer
- Yannis Xirotiris, Greek educator
- Yannis Yfantis, Greek writer and poet
- Giannis Zapropoulos, Greek footballer
- Giannis Zaradoukas, Greek footballer
- Yanis C. Yortsos, current Dean of the Viterbi School of Engineering at the University of Southern California
- Yanis Kanidis (1930–2004), a Greek-Russian physical education teacher
- Yanis Papassarantis (born 1988), a Belgian football player of Greek origin
- Yanis Smits, a Latvian theologian active against the Soviet rule over Latvia during 1956–1976
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