EIF3M

EIF3M
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3J8B, 3J8C, 5A5T
Identifiers
Aliases	EIF3M, B5, PCID1, TANGO7, hfl-B5, GA17, eukaryotic translation initiation factor 3 subunit M
External IDs	MGI: 1351744 HomoloGene: 4639 GeneCards: EIF3M
Gene ontology Molecular function • translation initiation factor binding • protein binding • translation initiation factor activity Cellular component • cytoplasm • eukaryotic 48S preinitiation complex • eukaryotic 43S preinitiation complex • eukaryotic translation initiation factor 3 complex • cytosol • eukaryotic translation initiation factor 3 complex, eIF3m Biological process • translational initiation • formation of translation preinitiation complex • regulation of translational initiation • cytoplasmic translational initiation • translation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10480	98221
Ensembl	ENSG00000149100	ENSMUSG00000027170
UniProt	Q7L2H7	Q99JX4
RefSeq (mRNA)	NM_001307929 NM_006360	NM_145380
RefSeq (protein)	NP_001294858.1 NP_006351.2	NP_663355.1
Location (UCSC)	Chr 11: 32.58 – 32.61 Mb	Chr 2: 105 – 105.02 Mb
PubMed search	[1]	[2]
Wikidata

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View/Edit Mouse

Eukaryotic translation initiation factor 3, subunit M (EIF3M) also known as PCI domain containing 1 (herpesvirus entry mediator)(PCID1), is a human gene.^[3][4]

HFLB5 encodes a broadly expressed protein containing putative membrane fusion domains that acts as a receptor or coreceptor for entry of herpes simplex virus (HSV).^[3][5]

See also

• Eukaryotic initiation factor 3 (eIF3)

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: PCID1 PCI domain containing 1 (herpesvirus entry mediator)".
4. Gawin B, Niederführ A, Schumacher N, Hummerich H, Little PF, Gessler M (November 1999). "A 7.5 Mb sequence-ready PAC contig and gene expression map of human chromosome 11p13-p14.1". Genome Res. 9 (11): 1074–86. doi:10.1101/gr.9.11.1074. PMC 310838. PMID 10568747.
5. Perez A, Li QX, Perez-Romero P, Delassus G, Lopez SR, Sutter S, McLaren N, Fuller AO (June 2005). "A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins". J. Virol. 79 (12): 7419–30. doi:10.1128/JVI.79.12.7419-7430.2005. PMC 1143644. PMID 15919898.

Further reading

• Kobayashi K, Xin Y, Ymer SI, et al. (2007). "Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells.". Brain Res. 1170: 129–39. doi:10.1016/j.brainres.2007.07.042. PMID 17719568.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Perez-Romero P, Fuller AO (2005). "The C terminus of the B5 receptor for herpes simplex virus contains a functional region important for infection.". J. Virol. 79 (12): 7431–7. doi:10.1128/JVI.79.12.7431-7437.2005. PMC 1143627. PMID 15919899.
• Perez A, Li QX, Perez-Romero P, et al. (2005). "A new class of receptor for herpes simplex virus has heptad repeat motifs that are common to membrane fusion proteins.". J. Virol. 79 (12): 7419–30. doi:10.1128/JVI.79.12.7419-7430.2005. PMC 1143644. PMID 15919898.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene. 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene. 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.