Tilmacoxib
Pharmacokinetic data | |
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Bioavailability | solution (64–88%) compared with capsule (22–40%). |
Identifiers | |
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PubChem (CID) | 159271 |
ChemSpider | 140082 |
UNII | G6VI5P84SX |
ChEBI | CHEBI:73041 |
ChEMBL | CHEMBL34913 |
Chemical and physical data | |
Formula | C16H19FN2O3S |
Molar mass | 338.397 g/mol |
3D model (Jmol) | Interactive image |
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Tilmacoxib or JTE-522 is a COX-2 inhibitor and is an effective chemopreventive agent against rat experimental liver fibrosis.[1]
See also
References
- ↑ Yamamoto, H., Kondo, M., Nakamori, S., Nagano, H., Wakasa, K., Sugita, Y., Chang-De, J., Kobayashi, S., Damdinsuren, B., Dono, K., Umeshita, K., Sekimoto, M., Sakon, M., Matsuura, N., Monden, M. (2003). "JTE-522, a cyclooxygenase-2 inhibitor, is an effective chemopreventive agent against rat experimental liver fibrosis1". Gastroenterology. 125 (2): 556–571. doi:10.1016/s0016-5085(03)00904-1. PMID 12891558.
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