Tunalikevirus
| Tunalikevirus | |
|---|---|
| Virus classification | |
| Group: | Group I (dsDNA) |
| Order: | Caudovirales |
| Family: | Siphoviridae |
| Subfamily: | Unassigned |
| Genus: | Tunalikevirus |
| Type species | |
| Enterobacteria phage T1 | |
Tunalikevirus (synonyms T1-like phages, T1-like viruses) is a genus of viruses in the order Caudovirales, in the family Siphoviridae. Bacteria serve as natural hosts. There are currently nine species in this genus, including the type species Enterobacteria phage T1.[1][2][3]
Taxonomy
Group: dsDNA
- Family: Siphoviridae
- Genus: Tunalikevirus
- Cronobacter phage Esp2949-1
- Enterobacter phage F20
- Enterobacteria phage T1
- Escherichia phage Eb49
- Escherichia phage Jk06
- Escherichia phage Rogue1
- Escherichia phage Rtp
- Escherichia phage Tls
- Shigella phage Shfl1
Structure
Tunalikeviruses are nonenveloped, with a head and tail. The head is about 60 nm in diameter. The tail is about 151 nm long, 8 nm wide. It's non-contractile, flexible, and has four short, kinked terminal fibers.[1]
| Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
|---|---|---|---|---|---|
| Tunalikevirus | Head-Tail | T=7 | Non-Enveloped | Linear | Monopartite |
Genome
Genomes are circular, around 50kb in length.[1] The type species, Enterobacteria phage T1, and five other species have been fully sequenced. They range between 45-51k nucleotides, with 45-87 proteins. The complete genomes, as well as two other similar, unclassified genomes are available here.[3]
Life cycle
Viral replication is cytoplasmic. The virus attaches to the host cell's adhesion receptor FhuA using its terminal fibers, and ejects the viral DNA into the host cytoplasm via long flexible tail ejection system. Replication follows the replicative transposition model. DNA-templated transcription is the method of transcription. Once the viral genes have been replicated, the procapsid is assembled and packed. The tail is then assembled and the mature virions are released via lysis, and holin/endolysin/spanin proteins. Bacteria serve as the natural host. Transmission routes are passive diffusion.[1]
| Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
|---|---|---|---|---|---|---|---|
| Tunalikevirus | Bacteria | None | Injection | Lysis | Cytoplasm | Cytoplasm | Passive diffusion |
History
According to ICTV's 1996 report, the genus Tunalikevirus was first accepted under the name T1-like phages, assigned only to family Siphoviridae. The whole family was moved to order Caudovirales in 1998, and the genus was renamed to T1-like viruses in ICTV's 7th Report in 1999. In 2012, it was renamed again to Tunalikevirus.[4]
References
- 1 2 3 4 "Viral Zone". ExPASy. Retrieved 1 July 2015.
- 1 2 ICTV. "Virus Taxonomy: 2014 Release". Retrieved 1 July 2015.
- 1 2 NCBI. "Tunalikevirus Complete Genomes". Retrieved 11 March 2015.
- ↑ ICTV. "Virus Taxonomy: 2014 Release". Retrieved 11 March 2015.