OR2L2

OR2L2
Identifiers
Aliases	OR2L2, HSHTPCRH07, HTPCRH07, OR1-48, OR2L12, OR2L4P, olfactory receptor family 2 subfamily L member 2
External IDs	MGI: 3030001 HomoloGene: 78689 GeneCards: OR2L2
Gene ontology Molecular function • molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • G-protein coupled receptor signaling pathway • biological process • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26246	258937
Ensembl	ENSG00000203663	ENSMUSG00000045341
UniProt	Q8NH16	n/a
RefSeq (mRNA)	NM_001004686	NM_146935
RefSeq (protein)	NP_001004686.1	n/a
Location (UCSC)	Chr 1: 248.04 – 248.04 Mb	Chr 16: 19.51 – 19.52 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Olfactory receptor 2L2 is a protein that in humans is encoded by the OR2L2 gene.^[3][4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[4]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. doi:10.1038/355453a0. PMID 1370859.
4. "Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family.". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR2L2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.