OR4B1

OR4B1
Identifiers
Aliases	OR4B1, OR11-106, OST208, olfactory receptor family 4 subfamily B member 1
External IDs	MGI: 109303 HomoloGene: 110550 GeneCards: OR4B1
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	119765	18331
Ensembl	ENSG00000175619	ENSMUSG00000075066
UniProt	Q8NGF8	n/a
RefSeq (mRNA)	NM_001005470	NM_010980
RefSeq (protein)	NP_001005470.1	n/a
Location (UCSC)	Chr 11: 48.22 – 48.22 Mb	Chr 2: 90.14 – 90.14 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Olfactory receptor 4B1 is a protein that in humans is encoded by the OR4B1 gene.^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: OR4B1 olfactory receptor, family 4, subfamily B, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4B1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.