OR52L1

OR52L1
Identifiers
Aliases	OR52L1, OR11-50, olfactory receptor family 52 subfamily L member 1
External IDs	MGI: 3030519 HomoloGene: 66455 GeneCards: OR52L1
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	338751	258160
Ensembl	ENSG00000183313	ENSMUSG00000047794
UniProt	Q8NGH7	n/a
RefSeq (mRNA)	NM_001005173	NM_001011857
RefSeq (protein)	NP_001005173.3	n/a
Location (UCSC)	Chr 11: 5.99 – 5.99 Mb	Chr 7: 105.18 – 105.18 Mb
PubMed search	[1]	[2]
Wikidata

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Olfactory receptor 52L1 is a protein that in humans is encoded by the OR52L1 gene.^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

See also

• Olfactory receptor

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: OR52L1 olfactory receptor, family 52, subfamily L, member 1".

Further reading

• Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR52L1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.