Otenabant
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Clinical data | |
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ATC code | none |
Identifiers | |
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CAS Number |
686344-29-6 ![]() |
PubChem (CID) | 10052040 |
ChemSpider |
8227602 ![]() |
UNII |
J8211Y53EF ![]() |
KEGG |
D09362 ![]() |
ChEMBL |
CHEMBL562668 ![]() |
Chemical and physical data | |
Formula | C25H25Cl2N7O |
Molar mass | 510.4 g/mol |
3D model (Jmol) | Interactive image |
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Otenabant (CP-945,598) is a drug which acts as a potent and highly selective CB1 antagonist.[1] It was developed by Pfizer for the treatment of obesity,[2] but development for this application has been discontinued following the problems seen during clinical use of the similar drug rimonabant.[3]
See also
References
- ↑ Kim, M.; et al. (2008), "Design, chemical synthesis, and biological evaluation of novel triazolyl analogues of taranabant (MK-0364), a cannabinoid-1 receptor inverse agonist" (PDF), Tetrahedron, 64 (48): 10802–10809, doi:10.1016/j.tet.2008.09.057
- ↑ Woods SC. The endocannabinoid system: novel pathway for cardiometabolic Risk-factor reduction. Journal of the American Academy of Physician Assistants. 2007 Nov;Suppl Endocannabinoid:7-10. PMID 18047036
- ↑ http://www.pfizer.com
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