ZNF644

ZNF644
Identifiers
Aliases	ZNF644, BM-005, MYP21, NatF, ZEP-2, zinc finger protein 644
External IDs	MGI: 1277212 HomoloGene: 12971 GeneCards: ZNF644
Gene ontology Molecular function • DNA binding • metal ion binding • nucleic acid binding Cellular component • nucleus Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	84146	52397
Ensembl	ENSG00000122482	ENSMUSG00000049606
UniProt	Q9H582	n/a
RefSeq (mRNA)	NM_016620 NM_032186 NM_201269	NM_026856
RefSeq (protein)	NP_057704.2 NP_115562.3 NP_958357.1	n/a
Location (UCSC)	Chr 1: 90.92 – 91.02 Mb	Chr 5: 106.62 – 106.7 Mb
PubMed search	[1]	[2]
Wikidata

View/Edit Human

View/Edit Mouse

Zing finger protein 644 (ZNF644) also known as zinc finger motif enhancer-binding protein 2 (Zep-2) is a protein that in humans is encoded by the ZNF644 gene.^[3]

Clinical relevance

Mutations in the ZNF644 gene have been found in sporadic cases of high myopia.^[4]

References

1. "Human PubMed Reference:".
2. "Mouse PubMed Reference:".
3. "Entrez Gene: zinc finger protein 644".
4. Shi, Yi (2011). "Exome Sequencing Identifies ZNF644 Mutations in High Myopia". PLoS Genetics. 7 (6): e1002084. doi:10.1371/journal.pgen.1002084.

Further reading

• Zabaneh D, Balding DJ (2010). "A genome-wide association study of the metabolic syndrome in Indian Asian men.". PLoS ONE. 5 (8): e11961. doi:10.1371/journal.pone.0011961. PMC 2915922. PMID 20694148.
• Mulligan P, Westbrook TF, Ottinger M, et al. (2008). "CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.". Mol. Cell. 32 (5): 718–26. doi:10.1016/j.molcel.2008.10.025. PMID 19061646.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
• Zhang QH, Ye M, Wu XY, et al. (2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.