Benorilate

Benorilate
Clinical data
Routes of
administration
Oral
ATC code N02BA10 (WHO)
Identifiers
CAS Number 5003-48-5 N
PubChem (CID) 21102
ChemSpider 19846 N
UNII W1QX9DV96G YesY
ChEMBL CHEMBL162036 N
Chemical and physical data
Formula C17H15NO5
Molar mass 313.305 g/mol
3D model (Jmol) Interactive image
 NYesY (what is this?)  (verify)

Benorilate (INN), or benorylate, is an ester-linked codrug of aspirin with paracetamol. It is used as an anti-inflammatory and antipyretic medication. In the treatment of childhood fever, it has been shown to be inferior to paracetamol and aspirin taken separately. In addition, because it is converted to aspirin, benorylate is not recommended in children due to concerns about Reye syndrome.[1]

References

  1. Simila S, Keinanen S, Kouvalainen K.Oral antipyretic therapy: evaluation of benorylate, an ester of acetylsalicylic acid and paracetamol. Eur J Pediatr. 1975 Dec 9;121(1):15-20. PMID 2478
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