2-MDP
Legal status | |
---|---|
Legal status |
|
Identifiers | |
| |
CAS Number | 33887-05-7 |
PubChem (CID) | 26538 |
ChemSpider | 24719 Y |
Chemical and physical data | |
Formula | C16H19NO |
Molar mass | 241.33 g·mol−1 |
3D model (Jmol) | Interactive image |
| |
| |
(verify) |
2-MDP (U-23807A) is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. The levo or (-) isomer is the active form of the drug.[1][2] It also has stimulant effects, having only around one third the potency of amphetamine by weight, but with a long duration of action, lasting more than 24 hours from a single oral dose.[3]
References
- ↑ Tang AH, Cangelosi AA, Code RA, Franklin SR. Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP). Pharmacology, Biochemistry and Behaviour. 1984 Feb;20(2):209-13.
- ↑ Blake JC, Davies SN, Church J, Martin D, Lodge D. 2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) selectively antagonises N-methyl-aspartate (NMA). Pharmacology, Biochemistry and Behaviour. 1986 Jan;24(1):23-5.
- ↑ John H Biel. Annual Reports in Medicinal Chemistry, Volume 2. Academic Press 1966. p18.
Receptor (ligands) |
| ||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transporter (blockers) |
| ||||||||||||||||||||||||||||||||||||||||||
Enzyme (inhibitors) |
| ||||||||||||||||||||||||||||||||||||||||||
Others |
| ||||||||||||||||||||||||||||||||||||||||||
See also: GABAergics • GHBergics • Glycinergics |
Stimulants (category) | |
---|---|
Adamantanes |
|
Adenosine antagonists | |
Alkylamines | |
Ampakines | |
Arylcyclohexylamines | |
Benzazepines | |
Cholinergics |
|
Convulsants | |
Eugeroics | |
Oxazolines | |
Phenethylamines |
|
Phenylmorpholines | |
Piperazines | |
Piperidines |
|
Pyrrolidines | |
Racetams | |
Tropanes |
|
Tryptamines | |
Others |
|
This article is issued from Wikipedia - version of the 4/2/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.